Gene

ahr1b

ID

ZDB-GENE-050922-1

Name

aryl hydrocarbon receptor 1b

Symbol

ahr1b Nomenclature History

Previous Names

ahr1 (1)
si:dkey-159d6.1

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Exhibits DNA-binding transcription factor activity, RNA polymerase II-specific and ligand-activated transcription factor activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II and response to xenobiotic stimulus. Predicted to localize to nucleus. Human ortholog(s) of this gene implicated in retinitis pigmentosa. Is expressed in eye. Orthologous to human AHR (aryl hydrocarbon receptor).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

3 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Ulin et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ahr1b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
retinitis pigmentosa 85	Alliance	?Retinitis pigmentosa 85	618345

Associated With ahr1b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000014	PAS domain
Domain	IPR011598	Myc-type, basic helix-loop-helix (bHLH) domain
Domain	IPR013655	PAS fold-3
Domain	IPR013767	PAS fold
Domain	IPR033348	Aryl hydrocarbon receptor, basic helix-loop-helix domain
Homologous_superfamily	IPR035965	PAS domain superfamily
Homologous_superfamily	IPR036638	Helix-loop-helix DNA-binding domain superfamily
Repeat	IPR001610	PAC motif