Gene

ptpn18

ID

ZDB-GENE-050320-12

Name

protein tyrosine phosphatase non-receptor type 18

Symbol

ptpn18 Nomenclature History

Previous Names

zgc:113105

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Description

Predicted to enable protein tyrosine phosphatase activity. Predicted to act upstream of or within protein dephosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human PTPN18 (protein tyrosine phosphatase non-receptor type 18).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6900525 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With ptpn18 Human Ortholog

No data available

Associated With ptpn18 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR016130	Protein-tyrosine phosphatase, active site
Domain	IPR000242	Tyrosine-specific protein phosphatase, PTPase domain
Domain	IPR000387	Tyrosine-specific protein phosphatases domain
Domain	IPR003595	Protein-tyrosine phosphatase, catalytic
Domain	IPR047254	Tyrosine-protein phosphatase non-receptor type 18, catalytic domain
Family	IPR047170	Tyrosine-protein phosphatase non-receptor type 12/18/22
Homologous_superfamily	IPR029021	Protein-tyrosine phosphatase-like