Gene
unc5b
- ID
- ZDB-GENE-041213-1
- Name
- unc-5 netrin receptor B
- Symbol
- unc5b Nomenclature History
- Previous Names
-
- sb:eu495
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have netrin receptor activity. Involved in branching involved in blood vessel morphogenesis and negative regulation of angiogenesis. Predicted to localize to integral component of membrane. Is expressed in several structures, including immature eye; nervous system; neural keel; pectoral fin bud; and trunk vasculature. Orthologous to human UNC5B (unc-5 netrin receptor B).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 22 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cssl:d832 (27 images)
- eu495 (10 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000488 | Death domain |
| Domain | IPR000906 | ZU5 domain |
| Domain | IPR003598 | Immunoglobulin subtype 2 |
| Domain | IPR003599 | Immunoglobulin domain subtype |
| Domain | IPR007110 | Immunoglobulin-like domain |
| Domain | IPR013098 | Immunoglobulin I-set |
| Domain | IPR033772 | UPA domain |
| Domain | IPR042156 | UNC5B, death domain |
| Family | IPR037936 | Netrin receptor UNC5 |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR013783 | Immunoglobulin-like fold |
| Homologous_superfamily | IPR036179 | Immunoglobulin-like domain superfamily |
| Homologous_superfamily | IPR036383 | Thrombospondin type-1 (TSP1) repeat superfamily |
| Repeat | IPR000884 | Thrombospondin type-1 (TSP1) repeat |
Domain Details Per Protein
| Protein | Length | Death domain | Death-like domain superfamily | Immunoglobulin domain subtype | Immunoglobulin I-set | Immunoglobulin-like domain | Immunoglobulin-like domain superfamily | Immunoglobulin-like fold | Immunoglobulin subtype 2 | Netrin receptor UNC5 | Thrombospondin type-1 (TSP1) repeat | Thrombospondin type-1 (TSP1) repeat superfamily | UNC5B, death domain | UPA domain | ZU5 domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
UniProtKB:A9JR35
|
940 | ||||||||||||||
|
UniProtKB:F1QXJ7
|
929 |
Interactions and Pathways
No data available
Plasmids