Gene
cox6a2
- ID
- ZDB-GENE-040912-129
- Name
- cytochrome c oxidase subunit 6A2
- Symbol
- cox6a2 Nomenclature History
- Previous Names
-
- zgc:103594 (1)
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Predicted to contribute to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen. Predicted to localize to mitochondrial respiratory chain complex IV. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease recessive intermediate D and cytochrome-c oxidase deficiency disease. Is expressed in brain; gill; heart; liver; and skeletal muscle. Orthologous to several human genes including COX6A2 (cytochrome c oxidase subunit 6A2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 3 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitochondrial complex IV deficiency nuclear type 18 | Alliance | Mitochondrial complex IV deficiency, nuclear type 18 | 619062 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cytochrome c oxidase, subunit VIa | Cytochrome c oxidase, subunit VIa, conserved site | Cytochrome c oxidase, subunit VIa superfamily |
|---|---|---|---|---|
|
UniProtKB:Q66I77
|
103 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cox6a2-202
(1)
|
Ensembl | 523 nt | ||
| ncRNA |
cox6a2-002
(1)
|
Ensembl | 677 nt |
Interactions and Pathways
No data available
Plasmids
No data available