Gene

sart3

ID
ZDB-GENE-040724-10
Name
spliceosome associated factor 3, U4/U6 recycling protein
Symbol
sart3 Nomenclature History
Previous Names
  • earl grey (1)
  • egy
  • p110 (1)
  • si:ch211-191d15.4
  • unm_sm471
  • wu:fc51h03
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to enable U6 snRNA binding activity and histone binding activity. Involved in spliceosomal snRNP assembly. Acts upstream of or within several processes, including exocrine pancreas development; spliceosomal complex assembly; and thymus development. Predicted to be located in Cajal body. Predicted to be part of ASAP complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human SART3 (spliceosome associated factor 3, U4/U6 recycling protein).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
14 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Allele Type Localization Consequence Mutagen Supplier
cz3Allele with one insertionUnknownUnknownENU
cz5Allele with one insertionUnknownUnknownENU
cz11Allele with one insertionUnknownUnknownENU
la010960TgTransgenic insertionUnknownUnknownDNA
la015580TgTransgenic insertionUnknownUnknownDNA
sa6968Allele with one point mutationUnknownPremature StopENU
sa31425Allele with one point mutationUnknownSplice SiteENU
sa33571Allele with one point mutationUnknownPremature StopENU
sm471Allele with one point mutationExon 6Premature StopENU
szy4Allele with one delinsExon 1UnknownCRISPR
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Sequence Targeting Reagents
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Human Disease
Associated With sart3 Human Ortholog
No data available
Associated With sart3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR008847 Suppressor of forked
Domain IPR034217 SART3, RNA recognition motif 1
Domain IPR034218 SART3, RNA recognition motif 2
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
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Domain Details Per Protein
Protein Length HAT (Half-A-TPR) repeat Nucleotide-binding alpha-beta plait domain superfamily RNA-binding domain superfamily RNA recognition motif domain SART3, RNA recognition motif 1 SART3, RNA recognition motif 2 Suppressor of forked Tetratricopeptide-like helical domain superfamily
UniProtKB:Q6ZM52 951
UniProtKB:B3DJT0 951
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Transcripts
Genome Browsers
Genome Build: GRCz11Chromosome: 5
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA sart3-201 (1) Ensembl 4,657 nt
mRNA sart3-202 (1) Ensembl 3,020 nt
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Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
No data available
Marker Relationships
Relationship Marker Type Marker Accession Numbers Citations
Contained inBACCH211-191D15
EncodesESTfc51h03ZFIN Curated Data
EncodesESTIMAGE:7151848Thisse et al., 2004
EncodescDNAMGC:171809ZFIN Curated Data
EncodescDNAMGC:195242ZFIN Curated Data
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Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Species Symbol Chromosome Accession # Evidence
HumanSART312
Conserved genome location (synteny) (2)
Amino acid sequence comparison (2)
MouseSart35
Conserved genome location (synteny) (1)
Amino acid sequence comparison (1)
Citations
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