Gene
pak4
- ID
- ZDB-GENE-040704-69
- Name
- p21 protein (Cdc42/Rac)-activated kinase 4
- Symbol
- pak4 Nomenclature History
- Previous Names
-
- im:5916170
- wu:fd12b01
- zgc:92014 (1)
- Type
- protein_coding_gene
- Location
- Chr: 15 Mapping Details/Browsers
- Description
- Predicted to have protein serine/threonine kinase activity. Involved in embryonic morphogenesis and myeloid leukocyte differentiation. Predicted to localize to cytoplasm. Is expressed in post-vent region. Orthologous to human PAK4 (p21 (RAC1) activated kinase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Law et al., 2013
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Binding_site | IPR017441 | Protein kinase, ATP binding site |
| Domain | IPR000095 | CRIB domain |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR033923 | p21 activated kinase binding domain |
| Family | IPR050285 | STE20 Serine/Threonine-Protein Kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036936 | CRIB domain superfamily |
Domain Details Per Protein
| Protein | Length | CRIB domain | CRIB domain superfamily | p21 activated kinase binding domain | Protein kinase, ATP binding site | Protein kinase domain | Protein kinase-like domain superfamily | STE20 Serine/Threonine-Protein Kinase |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1QZR2
|
664 |
Interactions and Pathways
No data available
Plasmids
No data available