ZFIN ID: ZDB-GENE-040704-69
Gene Name: p21 protein (Cdc42/Rac)-activated kinase 4
Gene Symbol: pak4    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: im:5916170, wu:fd12b01, zgc:92014 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Involved in embryonic morphogenesis and myeloid leukocyte differentiation. Predicted to localize to cytoplasm. Is expressed in post-vent region. Orthologous to human PAK4 (p21 (RAC1) activated kinase 4).
Genome Resources: Alliance (1),  Gene:431769 (1),  Ensembl(GRCz11):ENSDARG00000018110 (2)
GENE EXPRESSION
All Expression Data: Fig. 1 from Law et al., 2013
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
y276 Small Deletion Unknown Frameshift TALEN
y277 Small Deletion Exon 2 Frameshift TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-pak4 N/A 1
MO2-pak4 N/A 1
MO3-pak4 N/A 2
MO4-pak4 N/A 2
MO5-pak4 N/A 2
TALEN1-pak4 1
DISEASE ASSOCIATED WITH pak4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pak4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic morphogenesis (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pak4-201 (1)    Ensembl 5449
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES
Name Type Isotype Host Organism Assay Source Publications
Ab1-pak4 Rabbit WB 2
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pak4 No data available
MARKER RELATIONSHIPS
pak4 Contained in: [BAC] DKEY-54N8 (1) (order this)
pak4 Encodes: [EST] fd12b01 (1), IMAGE:5916170
[cDNA] MGC:92014 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001002222 (1) 5447 nt
Genomic GenBank:CU856359 (1) 216188 nt Blast at MegaBLAST
Polypeptide UniProtKB:F1QZR2 (1) 664 aa
Sequence Information (all 14)
ORTHOLOGY for pak4 ( Chr: 15 )
CITATIONS (25)