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ZIRC
ZFIN ID: ZDB-GENE-040704-69
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Gene Name: p21 protein (Cdc42/Rac)-activated kinase 4
Gene Symbol: pak4
Sequence Ontology ID : SO:0000704

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Previous Names: im:5916170, wu:fd12b01, zgc:92014 (1)

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(Including Attributions)
Location: Chr: 15 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Rac GTPase binding activity and protein serine/threonine kinase activity. Involved in embryonic morphogenesis and myeloid leukocyte differentiation. Predicted to localize to the  ...
GENE EXPRESSION
All Expression Data: Fig. 1 from Law et al., 2013
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
y276 Small Deletion Unknown Frameshift TALEN
y277 Small Deletion Exon 2 Frameshift TALEN
Targeting reagents:
PHENOTYPE
Data: 5 figures from 2 publications
Observed in:
DISEASE ASSOCIATED WITH pak4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH pak4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic morphogenesis (more)
Cellular Component cytoplasm (more)
Molecular Function ATP binding (more)
GO Terms (all 21)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000095 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR033923 (1)
  • InterPro:IPR036936 (1)
    		•
  • PROSITE:PS00107 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50108 (1)
    		•
  • Pfam:PF00069 (1)
  • Pfam:PF00786 (1)
    		•
  • EC:2.7.11.1 (1)
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pak4-201 (1) 5449
    Select Tool
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pak4 No data available
    MARKER RELATIONSHIPS
    pak4Contained in: [BAC] DKEY-54N8 (1) (order this)
    pak4Encodes: [EST] fd12b01 (1), IMAGE:5916170
    [cDNA] MGC:92014 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001002222 (1) 5447bp
    Select Tool
    Genomic GenBank:CU856359 (1) 216188bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1QZR2 (1) 664aa
    Select Tool
    Sequence Clusters UniGene:132625 (1)
    Sequence Information (all 15)
    OTHER pak4 GENE PAGES
  • Alliance (1)
  • Gene:431769 (1)
  • VEGA:OTTDARG00000040061 (1)
  • Ensembl(GRCz11):ENSDARG00000018110 (2)
    • ORTHOLOGY for pak4 (Chr: 15)
    CITATIONS (24)