Gene

pak4

ID
ZDB-GENE-040704-69
Name
p21 protein (Cdc42/Rac)-activated kinase 4
Symbol
pak4 Nomenclature History
Previous Names
  • im:5916170
  • wu:fd12b01
  • zgc:92014 (1)
Type
protein_coding_gene
Location
Chr: 15 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Involved in embryonic morphogenesis and myeloid leukocyte differentiation. Predicted to localize to cytoplasm. Is expressed in post-vent region. Orthologous to human PAK4 (p21 (RAC1) activated kinase 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Law et al., 2013
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With pak4 Human Ortholog
No data available
Associated With pak4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000095 CRIB domain
Domain IPR000719 Protein kinase domain
Domain IPR033923 p21 activated kinase binding domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR036936 CRIB domain superfamily
Domain Details Per Protein
Protein Length CRIB domain CRIB domain superfamily p21 activated kinase binding domain Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily
UniProtKB:Q6GMI1 663
UniProtKB:F1QZR2 664
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-pak4 Rabbit
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations