Gene

mtrex

ID

ZDB-GENE-040426-2854

Name

Mtr4 exosome RNA helicase

Symbol

mtrex Nomenclature History

Previous Names

mtrex
julie (1)
skiv2l2
wu:fd11a05
zgc:63838

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have RNA helicase activity. Involved in fin regeneration and positive regulation of cell division. Predicted to localize to nucleus. Is expressed in blastomere; nervous system; and pectoral fin. Orthologous to human MTREX (Mtr4 exosome RNA helicase).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Yang et al., 2007

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: 2 figures from Yang et al., 2007
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mtrex Human Ortholog

No data available

Associated With mtrex Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR001650	Helicase, C-terminal domain-like
Domain	IPR011545	DEAD/DEAH box helicase domain
Domain	IPR012961	ATP-dependent RNA helicase Ski2/MTR4, C-terminal
Domain	IPR014001	Helicase superfamily 1/2, ATP-binding domain
Domain	IPR025696	Exosome RNA helicase MTR4-like, beta-barrel domain
Domain	IPR048392	Exosome RNA helicase MTR4-like, stalk
Family	IPR016438	ATP-dependent RNA helicase SKI2-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase

Domain Details Per Protein

Protein	Length	ATP-dependent RNA helicase SKI2-like	ATP-dependent RNA helicase Ski2/MTR4, C-terminal	DEAD/DEAH box helicase domain	Exosome RNA helicase MTR4-like, beta-barrel domain	Exosome RNA helicase MTR4-like, stalk	Helicase, C-terminal domain-like	Helicase superfamily 1/2, ATP-binding domain	P-loop containing nucleoside triphosphate hydrolase
UniProtKB:Q6P7X6 InterPro	1034

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	mtrex-201 (1) Ensembl	Havana	3333 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	skiv2l2-002 (1) Ensembl	Havana	535 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations