Gene
naa10
- ID
- ZDB-GENE-040426-2648
- Name
- N-alpha-acetyltransferase 10, NatA catalytic subuni
- Symbol
- naa10 Nomenclature History
- Previous Names
-
- ard1a
- hm:zeh0223
- wu:fc66b08
- zgc:63981 (1)
- Type
- protein_coding_gene
- Location
- Chr: 23 Mapping Details/Browsers
- Description
- Exhibits peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal peptidyl-glutamic acid acetylation and N-terminal peptidyl-serine acetylation. Predicted to localize to NatA complex. Human ortholog(s) of this gene implicated in Ogden syndrome and syndromic microphthalmia. Is expressed in several structures, including alar plate midbrain region; brain; immature eye; musculature system; and pectoral fin bud. Orthologous to several human genes including NAA10 (N-alpha-acetyltransferase 10, NatA catalytic subunit).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:63981 (7 images)
Wild Type Expression Summary
- All Phenotype Data
- 4 figures from Ree et al., 2015
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Ogden syndrome | Alliance | Ogden syndrome | 300855 |
| syndromic microphthalmia 1 | Alliance | Microphthalmia, syndromic 1 | 309800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Acyl-CoA N-acyltransferase | GNAT domain | N-acetyltransferase Ard1-like |
|---|---|---|---|---|
|
UniProtKB:Q7T3B8
|
224 |
Interactions and Pathways
No data available
Plasmids
No data available