Gene
ilk
- ID
- ZDB-GENE-040426-1435
- Name
- integrin-linked kinase
- Symbol
- ilk Nomenclature History
- Previous Names
-
- loc
- lost-contact
- main squeeze
- msq
- zgc:65842
- zilk (1)
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Exhibits protein kinase activity. Involved in several processes, including circulatory system development; muscle attachment; and tendon development. Localizes to Z disc and sarcolemma. Predicted to colocalize with stress fiber. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in brain; cardiovascular system; muscle; myoblast; and somite. Orthologous to human ILK (integrin linked kinase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 12 figures from 8 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:65842 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 21 figures from 12 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain |
| Domain | IPR035692 | Integrin-linked protein kinase, pseudokinase domain |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036770 | Ankyrin repeat-containing domain superfamily |
| Repeat | IPR002110 | Ankyrin repeat |
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Integrin-linked protein kinase, pseudokinase domain | Protein kinase domain | Protein kinase-like domain superfamily | Serine-threonine/tyrosine-protein kinase, catalytic domain |
|---|---|---|---|---|---|---|---|
|
UniProtKB:Q6PHD6
|
452 |
Interactions and Pathways
No data available
Plasmids
No data available