ZFIN ID: ZDB-GENE-040426-1435
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Gene Name: integrin-linked kinase
Gene Symbol: ilk
Sequence Ontology ID : SO:0000704

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Previous Names: loc, lost-contact, main squeeze, msq, zgc:65842, zilk (1)

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Location: Chr: 10 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 12 figures from 8 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:65842]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
  blood vessel endothelial cell, brain, cardiac muscle cell Z disc, heart (all 15) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu801 Point Mutation Exon 10 Premature Stop
m347 Point Mutation Unknown Unknown ENU
Targeting reagents: MO1-ilk (2), MO2-ilk (2), MO3-ilk (1), MO4-ilk (1)
PHENOTYPE
Data: 15 figures from 9 publications
Observed in: blood, blood circulation, brain vasculature epithelium, brain vasculature (all 26) expand
DISEASE ASSOCIATED WITH ilk HUMAN ORTHOLOGNo data available
GENE ONTOLOGY
Ontology GO Term
Biological Process endothelial cell development (more)
Cellular Component Z disc (more)
Molecular Function protein kinase activity (more)
GO Terms (all 25)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719
  • InterPro:IPR001245
  • InterPro:IPR002110
  • InterPro:IPR011009
  • InterPro:IPR020683
    		•
  • PROSITE:PS50011
  • PROSITE:PS50088
  • PROSITE:PS50297
    		•
  • Pfam:PF07714
  • Pfam:PF12796
    		•
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ilk-001 (1) 3200
    Select Tool
    ncRNA ilk-002 (1) 803
    Select Tool
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Ab1-ilk (1), Ab2-ilk (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ilk No data available
    MARKER RELATIONSHIPS
    ilkContained in: [BAC] CH211-287A12 (1) (order this)
    ilkEncodes: [cDNA] MGC:65842 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_200571 (1) 3170bp
    Select Tool
    Genomic GenBank:AL928852 (1) 157466bp
    Select Tool
    Polypeptide UniProtKB:Q6PHD6 452aa
    Select Tool
    Sequence Clusters UniGene:77678 (1)
    Sequence Information (all 9)
    OTHER ilk GENE PAGES
  • Gene:393543 (1)
  • VEGA:OTTDARG00000019524 (1)
  • Ensembl(GRCz10):ENSDARG00000056964 (1)
    • ORTHOLOGY for ilk (Chr: 10)
    CITATIONS (34)