ZFIN ID: ZDB-GENE-040426-1435 |
Gene Name: | integrin-linked kinase | ||||||
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Gene Symbol: | ilk Nomenclature History | ||||||
Previous Names: | loc, lost-contact, main squeeze, msq, zgc:65842, zilk (1) | ||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 10 Mapping Details/Browsers | ||||||
Description: | Exhibits protein kinase activity. Involved in several processes, including circulatory system development; muscle attachment; and tendon development. Localizes to the Z disc and sarcolemma. Predicted to colocalize with the stress fiber. Human ortholog(s) of this gene implicated in pancreatic cancer. Is expressed in brain; cardiovascular system; muscle; myoblast; and somite. Orthologous to human ILK (integrin linked kinase). | ||||||
Genome Resources: | Alliance (1), Gene:393543 (1), Ensembl(GRCz11):ENSDARG00000056964 (2) |
All Expression Data: | 12 figures from 8 publications |
Directly Submitted Expression Data: | 1 figure (1 image) from Thisse et al., 2004 [MGC:65842] |
Wild-type Stages, Structures: | Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult) |
Curated Microarray Expression: | GEO (1) |
Ontology | GO Term |
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Biological Process | endothelial cell development (more) |
Cellular Component | cytoplasm (more) |
Molecular Function | protein kinase activity (more) |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
ilk-201
(1)
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3200 |
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ncRNA |
ilk-002
(1)
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803 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
Name | Type | Isotype | Host Organism | Assay | Source | Publications |
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Ab1-ilk | monoclonal | IgG2b | Mouse | IHC, WB |
Millipore
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3 |
Ab2-ilk | polyclonal | IgG | Rabbit | IHC |
GeneTex
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1 |
ilk Contained in: | [BAC] CH211-287A12 (1) (order this) |
ilk Encodes: | [cDNA] MGC:65842 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_200571 (1) | 3170 bp |
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Genomic | GenBank:AL928852 (1) | 157466 bp | |
Polypeptide | UniProtKB:Q6PHD6 (1) | 452 aa |
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Sequence Clusters | UniGene:77678 (1) |