Gene
mmp13a.1
- ID
- ZDB-GENE-031202-2
- Name
- matrix metallopeptidase 13a, tandem duplicate 1
- Symbol
- mmp13a.1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to enable metalloendopeptidase activity and zinc ion binding activity. Acts upstream of or within macrophage chemotaxis. Predicted to be located in extracellular matrix. Is expressed in several structures, including extension; heart; intermediate cell mass of mesoderm; leukocyte; and post-vent region. Human ortholog(s) of this gene implicated in anodontia; artery disease (multiple); bone disease (multiple); and ovarian carcinoma. Orthologous to human MMP13 (matrix metallopeptidase 13).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 56 figures from 45 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb1034 (5 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| spondyloepimetaphyseal dysplasia, Missouri type | Alliance | Metaphyseal anadysplasia 1 | 602111 |
| spondyloepimetaphyseal dysplasia, Missouri type | Alliance | ?Spondyloepimetaphyseal dysplasia, Missouri type | 602111 |
| Metaphyseal dysplasia, Spahr type | 250400 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
No data available
- Genome Browsers
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-mmp13a | polyclonal | IgG | Rabbit |
|
AnaSpec
|
4 |
Plasmids
No data available