Gene
ndrg1a
- ID
- ZDB-GENE-030826-34
- Name
- N-myc downstream regulated 1a
- Symbol
- ndrg1a Nomenclature History
- Previous Names
-
- ndrg1
- cb775 (1)
- wu:fb60h02
- zgc:63944
- Type
- protein_coding_gene
- Location
- Chr: 19 Mapping Details/Browsers
- Description
- Predicted to be involved in signal transduction. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4D. Is expressed in several structures, including integument; otic placode; pronephric mesoderm; pronephros; and visual system. Orthologous to human NDRG1 (N-myc downstream regulated 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 15 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb775 (14 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Takita et al., 2016
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Charcot-Marie-Tooth disease type 4D | Alliance | Charcot-Marie-Tooth disease, type 4D | 601455 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alpha/Beta hydrolase fold | NDRG |
|---|---|---|---|
|
UniProtKB:Q6A3P5
|
392 | ||
|
UniProtKB:A5WW18
|
379 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
ndrg1a-201
(1)
|
Ensembl | 2,353 nt | ||
| mRNA |
ndrg1a-202
(1)
|
Ensembl | 2,301 nt | ||
| ncRNA |
ndrg1a-003
(1)
|
Ensembl | 849 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-ndrg1a | Mouse |
|
1 | ||||
| Ab2-ndrg1a | Mouse |
|
1 | ||||
| Ab3-ndrg1a | Mouse |
|
1 |
Plasmids
No data available