Gene

pa2g4a

ID

ZDB-GENE-030616-161

Name

proliferation-associated 2G4, a

Symbol

pa2g4a Nomenclature History

Previous Names

pa2g4
si:dz150i12.2
wu:fb19b11
wu:ft56d05
zgc:86732

Type

protein_coding_gene

Location

Chr: 6 Mapping Details/Browsers

Description

Predicted to have nucleic acid binding activity. Predicted to localize to cytoplasm and nucleolus. Is expressed in several structures, including alar plate midbrain region; digestive system; nervous system; pectoral fin; and segmental plate. Orthologous to human PA2G4 (proliferation-associated 2G4).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

13 figures from 2 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

IMAGE:6911504 (12 images)
IMAGE:6907154 (10 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pa2g4a Human Ortholog

No data available

Associated With pa2g4a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Binding_site	IPR018349	Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site
Domain	IPR000994	Peptidase M24
Family	IPR004545	PA2G4 family
Family	IPR047113	Proliferation-associated protein 2G4/ARX1
Homologous_superfamily	IPR036005	Creatinase/aminopeptidase-like
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Creatinase/aminopeptidase-like	PA2G4 family	Peptidase M24	Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site	Proliferation-associated protein 2G4/ARX1	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:Q8AW82 InterPro PDB	392

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	pa2g4a-001 (1)	Havana	2363 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	pa2g4a-201 (1) Ensembl	Havana	2476 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations