Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030219-92
Gene Name: zic family member 2 (odd-paired homolog, Drosophila) b
Gene Symbol: zic2b
Previous Names: zic2.2 (1), zic2l, hm:zeh0655, id:ibd5017
Location: Chr: 1   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 11 figures from 8 publications
Directly Submitted Expression Data: 4 figures (5 images) from Kudoh et al., 2001 [ibd5017]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
  anterior neural keel lateral region, anterior neural rod lateral region, cranial neural crest, epiblast (all 17) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la028121Tg, la028122Tg
Knockdown reagents: MO1-zic2b (1), MO2-zic2b (1)
PHENOTYPE
Data: 5 figures from Teslaa et al., 2013
Observed in: cranial neural crest, embryonic viscerocranium morphogenesis, forebrain development, melanoblast (all 16) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Holoprosencephaly-5 609637
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic viscerocranium morphogenesis (more)
Molecular Function metal ion binding (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007087 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR015880 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA zic2b-001 (1) 2248
    ncRNA zic2b-002 (1) 693
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM zic2b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    zic2b Contained in: [BAC] DKEY-256M19 (1)
    zic2b Contains: [SNP] rs3727533 (1), rs3727534 (1)
    zic2b Encodes: [EST] ibd5017 (order this), zeh0655
    [cDNA] MGC:110428 (1) (order this), MGC:198352 (1) (order this), MGC:198356 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001820 (1) 2239 bp
    Genomic GenBank:BX088652 (1) 161341 bp
    Select Tool
    Polypeptide UniProtKB:Q9DE40 (1) 427 aa
    Sequence Clusters UniGene:76511 (1)
    Sequence Information (all 23)
    OTHER zic2b GENE PAGES
  • Gene:570746 (1)
  • VEGA:OTTDARG00000027069 (1)
  • Ensembl(Zv9):ENSDARG00000037178 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish zic2b 1  
    Human ZIC2 13 (13q32)
  • OMIM:603073
  • Gene:7546
  • Mouse Zic2 14 ( 65.97 cM)
  • MGI:106679
  • Gene:22772
  • Orthology Details
    CITATIONS (31)