ZFIN ID: ZDB-GENE-030219-92
Gene Name: zic family member 2 (odd-paired homolog, Drosophila) b
Gene Symbol: zic2b

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Previous Names: zic2.2 (1), zic2l, hm:zeh0655, id:ibd5017

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Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 9 publications
Directly Submitted Expression Data: 4 figures (5 images) from Kudoh et al., 2001 [ibd5017]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Pharyngula:Prim-5 (24.0h-30.0h)
  anterior neural keel lateral region, anterior neural rod lateral region, cranial neural crest, epiblast (all 24) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028121Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028122Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32696 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-zic2b (1), MO2-zic2b (1)
    PHENOTYPE
    Data: 5 figures from Teslaa et al., 2013
    Observed in: cranial neural crest, embryonic viscerocranium morphogenesis, forebrain development, melanoblast (all 16) expand
    DISEASE ASSOCIATED WITH zic2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly Holoprosencephaly 5 609637
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hindbrain development (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007087 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR015880 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA zic2b-001 (1) 2248
    ncRNA zic2b-002 (1) 693
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM zic2b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    zic2bContained in: [BAC] DKEY-256M19 (1) (order this)
    zic2bContains: [SNP] rs3727533 (1), rs3727534 (1)
    zic2bEncodes: [EST] ibd5017 (order this), zeh0655
    [cDNA] MGC:110428 (1) (order this), MGC:198352 (1) (order this), MGC:198356 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001820 (1) 2239bp
    Genomic GenBank:BX088652 (1) 161341bp
    Select Tool
    Polypeptide UniProtKB:Q9DE40 (1) 427aa
    Sequence Clusters UniGene:76511 (1)
    Sequence Information (all 23)
    OTHER zic2b GENE PAGES
  • Gene:570746 (1)
  • VEGA:OTTDARG00000027069 (1)
  • Ensembl(GRCz10):ENSDARG00000037178 (1)
  • ORTHOLOGY for zic2b (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human ZIC2 13
  • Gene:7546
  • OMIM:603073
  • HGNC:12873
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Zic2 14
  • MGI:106679
  • Gene:22772
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (36)