ZFIN ID: ZDB-GENE-030219-92
Gene Name: zic family member 2 (odd-paired homolog, Drosophila) b
Gene Symbol: zic2b
Previous Names: zic2.2 (1), zic2l, hm:zeh0655, id:ibd5017
Location: Chr: 1 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 13 figures from 9 publications
Directly Submitted Expression Data: 4 figures (5 images) from Kudoh et al., 2001 [ibd5017]
Wild-type Stages, Structures: Blastula:30%-epiboly (4.66h-5.25h) to Pharyngula:Prim-5 (24.0h-30.0h)
  anterior neural keel lateral region, anterior neural rod lateral region, cranial neural crest, epiblast (all 24) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Mutagen Suppliers
la028121Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028122Tg Transgenic Insertion DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-zic2b (1), MO2-zic2b (1)
    PHENOTYPE
    Data: 5 figures from Teslaa et al., 2013
    Observed in: cranial neural crest, embryonic viscerocranium morphogenesis, forebrain development, melanoblast (all 16) expand
    DISEASE ASSOCIATED WITH zic2b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly Holoprosencephaly-5 609637
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process hindbrain development (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR007087 (1)
  • InterPro:IPR013087 (1)
  • InterPro:IPR015880 (1)
  • PROSITE:PS00028 (1)
  • PROSITE:PS50157 (1)
  • Pfam:PF00096 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA zic2b-001 (1) 2248
    ncRNA zic2b-002 (1) 693
    GENE PRODUCT DESCRIPTION No description available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM zic2b No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    zic2bContained in: [BAC] DKEY-256M19 (1) (order this)
    zic2bContains: [SNP] rs3727533 (1), rs3727534 (1)
    zic2bEncodes: [EST] ibd5017 (order this), zeh0655
    [cDNA] MGC:110428 (1) (order this), MGC:198352 (1) (order this), MGC:198356 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001001820 (1) 2239bp
    Genomic GenBank:BX088652 (1) 161341bp
    Select Tool
    Polypeptide UniProtKB:Q9DE40 (1) 427aa
    Sequence Clusters UniGene:76511 (1)
    Sequence Information (all 23)
    OTHER zic2b GENE PAGES
  • Gene:570746 (1)
  • VEGA:OTTDARG00000027069 (1)
  • Ensembl(GRCz10):ENSDARG00000037178 (1)
  • ORTHOLOGY for zic2b (Chr: 1)
    Species Symbol Chromosome Accession # Evidence
    Human ZIC2 13
  • Gene:7546
  • OMIM:603073
  • HGNC:12873
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Zic2 14
  • MGI:106679
  • Gene:22772
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (33)