Gene
cyfip1
- ID
- ZDB-GENE-030131-8557
- Name
- cytoplasmic FMR1 interacting protein 1
- Symbol
- cyfip1 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to enable RNA 7-methylguanosine cap binding activity and actin filament binding activity. Acts upstream of or within with a positive effect on axon extension. Predicted to be located in cytoplasm. Predicted to be part of SCAR complex. Predicted to be active in neuron projection and synapse. Is expressed in dorsal telencephalon. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7144298 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Cioni et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | CYRIA/CYRIB, Rac1 binding domain | Cytoplasmic FMR1-interacting |
|---|---|---|---|
|
UniProtKB:Q90YM8
|
1253 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
cyfip1-201
(1)
|
Ensembl | 4,645 nt | ||
| mRNA |
cyfip1-202
(1)
|
Ensembl | 1,654 nt | ||
| ncRNA |
cyfip1-003
(1)
|
Ensembl | 510 nt | ||
| ncRNA |
cyfip1-004
(1)
|
Ensembl | 515 nt |
Interactions and Pathways
No data available
Plasmids
No data available