Gene

jun

ID

ZDB-GENE-030131-7859

Name

Jun proto-oncogene, AP-1 transcription factor subunit

Symbol

jun Nomenclature History

Previous Names

c-jun (1)
fj36h07
wu:fj36h07
zgc:65863 (1)

Type

protein_coding_gene

Location

Chr: 20 Mapping Details/Browsers

Description

Contributes to DNA-binding transcription factor activity and beta-catenin binding activity. Involved in several processes, including canonical Wnt signaling pathway; response to cadmium ion; and response to methylmercury. Localizes to transcription factor complex. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Is expressed in several structures, including digestive system; hematopoietic system; mesoderm; musculature system; and sensory system. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

31 figures from 22 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:77457 (19 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Gan et al., 2008
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With jun Human Ortholog

No data available

Associated With jun Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR004827	Basic-leucine zipper domain
Domain	IPR005643	Jun-like transcription factor
Family	IPR002112	Transcription factor Jun
Family	IPR050946	AP-1 Transcription Factor bZIP
Homologous_superfamily	IPR008917	Transcription factor, Skn-1-like, DNA-binding domain superfamily
Homologous_superfamily	IPR046347	Basic-leucine zipper domain superfamily