Gene

jun

ID
ZDB-GENE-030131-7859
Name
Jun proto-oncogene, AP-1 transcription factor subunit
Symbol
jun Nomenclature History
Previous Names
  • c-jun (1)
  • fj36h07
  • wu:fj36h07
  • zgc:65863 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Contributes to DNA-binding transcription factor activity and beta-catenin binding activity. Involved in several processes, including canonical Wnt signaling pathway; response to cadmium ion; and response to methylmercury. Localizes to transcription regulator complex. Is expressed in several structures, including digestive system; hematopoietic system; mesoderm; musculature system; and sensory system. Human ortholog(s) of this gene implicated in pulmonary tuberculosis. Orthologous to human JUN (Jun proto-oncogene, AP-1 transcription factor subunit).
Genome Resources
Note
None
Expression
All Expression Data
21 figures from 13 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 3 from Gan et al., 2008
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With jun Human Ortholog
No data available
Associated With jun Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR004827 Basic-leucine zipper domain
Domain IPR005643 Jun-like transcription factor
Family IPR002112 Transcription factor Jun
Family IPR015558 Transcription Factor c-Jun/v-Jun
Homologous_superfamily IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Basic-leucine zipper domain Jun-like transcription factor Transcription Factor c-Jun/v-Jun Transcription factor Jun Transcription factor, Skn-1-like, DNA-binding domain superfamily
UniProtKB:Q6NZT5 308
UniProtKB:Q4ZJE9 308
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-jun polyclonal Rabbit
  • IHC
Cell Signaling Technology, Inc.
4
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations