ZFIN Gene: aldh18a1

ZFIN ID: ZDB-GENE-030131-5602

ZFIN ID: ZDB-GENE-030131-5602

Gene Name:	aldehyde dehydrogenase 18 family, member A1
Gene Symbol:	aldh18a1
Previous Names:	cb842 (1), cb899 (1), pycs (1), sb:cb881, wu:fa91f10, wu:fi05f11, wu:fi17d12
Nomenclature History

GENE EXPRESSION
Directly Submitted Expression Data:	12 figures (29 images) from Rauch et al., 2003 [fi50d09]
	4 figures (5 images) from Thisse et al., 2001 [cb899]
	6 figures (14 images) from Thisse et al., 2004 [IMAGE:7165398]
	5 figures (12 images) from Thisse et al., 2001 [cb842]
	4 figures (3 images) from Thisse et al., 2001 [cb881]
Wild-type Stages, Structures:	Cleavage:2-cell (0.75h-1.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
	alar plate midbrain region , brain , endocrine system , epidermis (all 22)
Curated Microarray Expression:	GEO (1)

MUTANTS AND TARGETED KNOCKDOWNS

Alleles:	la018205Tg
Knockdown reagents:	MO1-aldh18a1 (1)

PHENOTYPE

Phenotype of Human Orthologue	OMIM Phenotype ID
Cutis laxa, autosomal recessive, type IIIA	219150

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cellular amino acid biosynthetic process (more)
Cellular Component	cytoplasm (more)
Molecular Function	catalytic activity (more)

GO Terms (all 11)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR000965 (1) InterPro:IPR001048 (1) InterPro:IPR001057 (1) InterPro:IPR005715 (1) InterPro:IPR005766 (1) InterPro:IPR015590 (1) InterPro:IPR016161 (1) InterPro:IPR016162 (1) InterPro:IPR016163 (1) InterPro:IPR019797 (1) InterPro:IPR020593 (1)	PROSITE:PS00902 (1) PROSITE:PS01223 (1)	Pfam:PF00171 (1) Pfam:PF00696 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	aldh18a1-001 (1)	4203	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega

GENE PRODUCT DESCRIPTION

ANTIBODIES No data available

CONSTRUCTS WITH SEQUENCES FROM aldh18a1 No data available

SEGMENT (CLONE AND PROBE) RELATIONSHIPS

aldh18a1 Contained in:	[BAC] DKEY-41E15 (1) (order this)
aldh18a1 Contains:	[SNP] rs3728509 (1)
aldh18a1 Encodes:	[EST] cb842 (1) (order this), cb881 (1) (order this), cb899 (1) (order this), fa91f10, fi05f11, fi17d12, fi50d09 (1) (order this), IMAGE:7165398 (1) (order this) [cDNA] MGC:162616 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001083546 (1)	4424 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT Vega
Genomic	GenBank:CR751608 (1)	209340 bp	Blast at MegaBLAST
Polypeptide	UniProtKB:E7EZW8 (1)	784 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast Vega Protein Blast
Sequence Clusters	UniGene:76195 (1)

OTHER aldh18a1 GENE PAGES

Gene:557186 (1)

VEGA:OTTDARG00000027405 (1)

Ensembl(Zv9):ENSDARG00000061123 (1)

MAPPING INFORMATION
Chr: 12, 13 Details

ORTHOLOGY

CITATIONS (22)