Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-030131-2908
Gene Name: cytochrome P450, family 26, subfamily b, polypeptide 1
Gene Symbol: cyp26b1
Previous Names: dol, fc21d03, stocksteif (1), wu:fc21d03, wu:fc26h10, zgc:76999
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 17 publications
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Adult (90d-730d, breeding adult)
  ceratobranchial cartilage perichondrium, ceratohyal cartilage perichondrium, cerebellum, chondroblast distal_to (all 47) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 8 genotypes
Alleles: la025910Tg, sa2, sa3, t24295, ti230g
Knockdown reagents: MO1-cyp26b1 (1), MO2-cyp26b1 (1), MO3-cyp26b1 (1), MO4-cyp26b1 (1), MO5-cyp26b1 (1)
PHENOTYPE
Data: 19 figures from 7 publications
Observed in: basibranchial, basihyal cartilage, bone element, cartilage development (all 54) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Craniosynostosis with radiohumeral fusions and other skeletal and craniofacial anomalies 614416
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of retinoic acid receptor signaling pathway (more)
Cellular Component endoplasmic reticulum (more)
Molecular Function 1-hydroxypyrene 6,7-monooxygenase activity (more)
GO Terms (all 58)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001128 (1)
  • InterPro:IPR002403 (1)
  • InterPro:IPR017972 (1)
  • PROSITE:PS00086 (1)
  • Pfam:PF00067 (1)
  • EC:1.14.-.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cyp26b1-001 (1) 3869
    ncRNA cyp26b1-002 (1) 579
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cyp26b1
    TgBAC(cyp26b1:Citrine)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cyp26b1 Contained in: [BAC] CH73-51F7 (1) (order this), CH73-368P22 (1) (order this), CH211-197C14 (order this)
    cyp26b1 Encodes: [EST] fc21d03, fc26h10 (1)
    [cDNA] MGC:76999 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_212666 (1) 3348 bp
    Genomic GenBank:AL935122 198363 bp
    Select Tool
    Polypeptide UniProtKB:Q6EIG3 (1) 511 aa
    Sequence Clusters UniGene:76359 (1)
    Sequence Information (all 17)
    OTHER cyp26b1 GENE PAGES
  • Gene:324188 (1)
  • VEGA:OTTDARG00000035532 (1)
  • Ensembl(Zv9):ENSDARG00000077121 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish cyp26b1 7  
    Human CYP26B1 2 (2p13.2)
  • OMIM:605207
  • Gene:56603
  • Mouse Cyp26b1 6 ( 36.45 cM)
  • MGI:2176159
  • Gene:232174
  • Orthology Details
    CITATIONS (55)