Gene

gabpa

ID

ZDB-GENE-011010-2

Name

GA binding protein transcription factor subunit alpha

Symbol

gabpa Nomenclature History

Previous Names

e4tf
wu:fc12d11 (1)

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Description

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific. Predicted to be involved in cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in endothelial cell and telencephalon. Orthologous to human GABPA (GA binding protein transcription factor subunit alpha).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

4 figures from 3 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:66115 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With gabpa Human Ortholog

No data available

Associated With gabpa Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000418	Ets domain
Domain	IPR003118	Pointed domain
Domain	IPR024668	GA-binding protein alpha subunit, N-terminal
Family	IPR016312	Transcription factor, GA-binding, alpha subunit
Family	IPR046328	ETS family
Homologous_superfamily	IPR013761	Sterile alpha motif/pointed domain superfamily
Homologous_superfamily	IPR029071	Ubiquitin-like domain superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	Ets domain	ETS family	GA-binding protein alpha subunit, N-terminal	Pointed domain	Sterile alpha motif/pointed domain superfamily	Transcription factor, GA-binding, alpha subunit	Ubiquitin-like domain superfamily	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:Q9I9E8 InterPro	455

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	gabpa-201 (1) Ensembl	Ensembl	1,914 nt	Select Tool ZFIN BLAST
mRNA	gabpa-202 (1) Ensembl	Ensembl	1,931 nt	Select Tool ZFIN BLAST
mRNA	gabpa-204 (1) Ensembl	Ensembl	1,007 nt	Select Tool ZFIN BLAST
mRNA	gabpa-205 (1) Ensembl	Ensembl	1,644 nt	Select Tool ZFIN BLAST
mRNA	gabpa-206 (1) Ensembl	Ensembl	2,879 nt	Select Tool ZFIN BLAST
ncRNA	gabpa-004 (1) Ensembl	Ensembl	771 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations