Gene

celf1

ID

ZDB-GENE-000501-1

Name

cugbp, Elav-like family member 1

Symbol

celf1 Nomenclature History

Previous Names

brul (1)
Bruno-like (1)
cb920 (1)
cugbp1
im:7151366 (1)
si:dkey-30l20.6

Type

protein_coding_gene

Location

Chr: 7 Mapping Details/Browsers

Description

Enables mRNA 3'-UTR binding activity. Involved in cell migration; liver development; and pancreas morphogenesis. Acts upstream of or within several processes, including embryonic liver development; endodermal digestive tract morphogenesis; and positive regulation of mRNA catabolic process. Located in pole plasm. Is expressed in several structures, including eye; gonad; lens placode; pectoral fin; and solid lens vesicle. Orthologous to human CELF1 (CUGBP Elav-like family member 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

21 figures from 11 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

cb920 (6 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 13 figures from 3 publications
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With celf1 Human Ortholog

No data available

Associated With celf1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000504	RNA recognition motif domain
Domain	IPR034196	CELF1/2, RNA recognition motif 1
Domain	IPR034198	CELF1/2, RNA recognition motif 2
Domain	IPR034199	CELF1/2, RNA recognition motif 3
Family	IPR002343	Paraneoplastic encephalomyelitis antigen
Homologous_superfamily	IPR012677	Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily	IPR035979	RNA-binding domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9Q1S9	InterPro	511
UniProtKB:A0A8M3B493	InterPro	508
UniProtKB:A0A8M2BGC2	InterPro	522
UniProtKB:A0A8M3AUE5	InterPro	530
UniProtKB:A0A8M3B1C7	InterPro	507
UniProtKB:A0A8M2BGA2	InterPro	535
UniProtKB:A0A8M2BGA1	InterPro	539
UniProtKB:A0A8M3B1C3	InterPro	542
UniProtKB:Q9IBD0	InterPro	501
UniProtKB:A0A8M2BGA3	InterPro	518
UniProtKB:A0A8M3AUE9	InterPro	504
UniProtKB:A0A8M3AUD4	InterPro	526
UniProtKB:A0A8M2BGX4	InterPro	519
UniProtKB:A0A8M2BGB8	InterPro	523
UniProtKB:A0A8M9QH64	InterPro	535
UniProtKB:A0A8M9PP42	InterPro	512
UniProtKB:A0A8M3BB44	InterPro	545
UniProtKB:A0A8M3B487	InterPro	545
UniProtKB:A0A8M3AUE0	InterPro	546
UniProtKB:A0A8M3BB48	InterPro	529

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	celf1-201 (1) Ensembl	Ensembl	2,778 nt	Select Tool ZFIN BLAST
mRNA	celf1-202 (1) Ensembl	Ensembl	3,709 nt	Select Tool ZFIN BLAST
mRNA	celf1-203 (1) Ensembl	Ensembl	827 nt	Select Tool ZFIN BLAST
mRNA	celf1-204 (1) Ensembl	Ensembl	779 nt	Select Tool ZFIN BLAST
ncRNA	si:dkey-30l20.6-001 (1) Ensembl	Ensembl	1,128 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

Name	Type	Antigen Genes	Isotype	Host Organism	Assay	Source	Citations
Ab1-cugbp1	polyclonal	celf1		Rabbit			2

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations