ZFIN ID: ZDB-GENE-000501-1
Gene Name: cugbp, Elav-like family member 1
Gene Symbol: celf1    Nomenclature History

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Previous Names: brul (1), Bruno-like (1), cb920 (1), cugbp1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Exhibits mRNA 3'-UTR binding activity. Involved in several processes, including animal organ development; endodermal digestive tract morphogenesis; and positive regulation of mRNA catabolic process. Localizes to pole plasm. Is expressed in several structures, including eye; gonad; lens placode; pectoral fin; and solid lens vesicle. Orthologous to human CELF1 (CUGBP Elav-like family member 1).
Genome Resources: Alliance (1),  Gene:58137 (1),  Ensembl(GRCz11):ENSDARG00000005315 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la011273Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026044Tg Transgenic Insertion Unknown Unknown DNA
    sa1640 Point Mutation Unknown Premature Stop ENU
    sa11143 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21022 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-celf1 N/A 2
    MO2-celf1 N/A 2
    MO3-celf1 N/A 1
    DISEASE ASSOCIATED WITH celf1 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH celf1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell migration (more)
    Cellular Component cytoplasm (more)
    Molecular Function mRNA binding (more)
    GO Terms (all 23)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA celf1-201 (1)    Ensembl 2778
    celf1-202 (1)    Ensembl 3709
    celf1-203 (1)    Ensembl 827
    celf1-204 (1)    Ensembl 779
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-cugbp1 polyclonal Rabbit 2
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM celf1
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(-1.2celf1:EGFP) celf1 EGFP Danio rerio 1 1
    MARKER RELATIONSHIPS
    celf1 Contained in: [BAC] CH211-274E20 (1), DKEY-30L20 (1) (order this)
    celf1 Encodes: [EST] cb920 (1) (order this)
    [cDNA] MGC:56472 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131613 (1) 2538 nt
    Genomic GenBank:CR318601 (1) 165501 nt
    Select Tool
    Polypeptide UniProtKB:Q9IBD0 (1) 501 aa
    Sequence Information (all 60)
    ORTHOLOGY for celf1 ( Chr: 7 )
    CITATIONS (46)