| ZFIN ID: ZDB-GENE-000125-4 |
| Gene Name: | deltaC |
|---|---|
| Gene Symbol: | dlc |
| Previous Names: | bea, beamter |
| All Expression Data: | 97 figures from 58 publications |
| Directly Submitted Expression Data: | 6 figures (26 images) from Thisse et al., 2005 [eu289] |
| 6 figures (20 images) from Thisse et al., 2008 [cssl:d401] | |
| 6 figures (18 images) from Thisse et al., 2005 [eu238] | |
| Wild-type Stages, Structures: | Blastula:30%-epiboly (4.66h-5.25h) to Adult (90d-730d, breeding adult) |
|---|---|
alar plate midbrain region,
brain,
cardiovascular system,
central nervous system
|
|
| Curated Microarray Expression: | GEO (1) |
| Mutant lines: | 15 genotypes |
| Alleles: |
b663,
dlc_unspecified,
la012690Tg,
thf102,
tit446
|
| Knockdown reagents: |
MO1-dlc
(1),
MO2-dlc
(1),
MO3-dlc
(1),
MO4-dlc
(1),
MO5-dlc
(1)
|
| Data: | 15 figures from 7 publications |
| Observed in: |
blood,
determination of left/right asymmetry in lateral mesoderm,
ectoderm development,
hematopoietic stem cell
|
| Phenotype of Human Orthologue | OMIM Phenotype ID |
|---|---|
| Spondylocostal dysostosis, autosomal recessive, 1 | 277300 |
| Ontology | GO Term |
|---|---|
| Biological Process | hematopoietic stem cell differentiation (more) |
| Cellular Component | cytoplasm (more) |
| Molecular Function | PDZ domain binding (more) |
|
|
|
|
| Type | Name | Length (bp) | Analysis | |
|---|---|---|---|---|
| mRNA | dlc-001 (1) | 3567 |
Select Tool
|
|
| ncRNA | dlc-002 (1) | 728 |
Select Tool
|
| Tg(UAS:dlc) |
| dlc Contained in: | [BAC] DKEY-46I14 (1) (order this) |
| dlc Encodes: |
[EST]
eu238 (1),
eu289 (1)
[cDNA] cssl:d401 (1) (order this), MGC:193544 (1) (order this), MGC:193551 (1) (order this) |
| Type | Accession # | Length (bp/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_130944 (1) | 3610 bp |
Select Tool
|
| Genomic | GenBank:CR626887 (1) | 198090 bp | |
| Polypeptide | UniProtKB:Q9IAT6 (1) | 664 aa |
Select Tool
|
| Sequence Clusters | UniGene:81314 (1) |
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| Chr: 15 Details | View Map: Merged Individual Panels |
| Evidence | ||||||
|---|---|---|---|---|---|---|
| Species | Symbol | Chromosome (Position) | Accession # | AA | CL | |
| Zebrafish | dlc | 15 |
|
|
||
| Human | DLL3 | 19 (19q13) |
|
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|
Request: 