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General Information
ZIRC
ZFIN ID: ZDB-GENE-980526-501
Gene Name: T-cell acute lymphocytic leukemia 1
Gene Symbol: tal1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA binding IMP Juarez et al., 2005
DNA-binding transcription factor activity, RNA polymerase II-specific IBA PANTHER:PTN001015390, MGI:MGI:98480 Gaudet et al., 2010
protein dimerization activity IEA InterPro:IPR011598 ZFIN Electronic Annotation
protein dimerization activity IEA InterPro:IPR036638 ZFIN Electronic Annotation
RNA polymerase II regulatory region sequence-specific DNA binding IBA PANTHER:PTN001015390, UniProtKB:Q02575 Gaudet et al., 2010
sequence-specific DNA binding IDA Schupp et al., 2014
Cellular Component nucleus IC DNA binding Juarez et al., 2005
nucleus IBA PANTHER:PTN001015390, UniProtKB:P17542, MGI:MGI:98480 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process angiogenesis IEA UniProtKB-KW:KW-0037 ZFIN Electronic Annotation
angiogenesis IMP MO2-tal1, MO1-tal1 Dooley et al., 2005
artery morphogenesis IMP Patterson et al., 2005
artery morphogenesis IMP tal1t21384/t21384 (TU) Bussmann et al., 2007
blood vessel development IGI MO1-mtmr8, tal1 Mei et al., 2010
blood vessel development IMP MO4-tal1 2 Publications
cell differentiation IEA UniProtKB-KW:KW-0221 ZFIN Electronic Annotation
definitive hemopoiesis IMP 3 Publications
embryonic heart tube development IMP tal1t21384/t21384 (TU) Bussmann et al., 2007
embryonic hemopoiesis IMP MO4-tal1 2 Publications
embryonic hemopoiesis IMP MO4-tal1, MO1-tal1 Liu et al., 2006
embryonic hemopoiesis IMP MO7-tal1 Xiong et al., 2008
embryonic hemopoiesis IMP MO8-tal1 Zhen et al., 2013
endocardium formation IMP Bussmann et al., 2007
endocardium morphogenesis IMP MO5-tal1, MO6-tal1 Schumacher et al., 2013
erythrocyte differentiation IEP Qian et al., 2007
erythrocyte differentiation IGI lmo2 Gering et al., 2003
heart development IGI MO4-tal1, MO2-etv2 Simões et al., 2011
heart morphogenesis IGI etv2 Schoenebeck et al., 2007
hemangioblast cell differentiation IDA Gering et al., 1998
hemangioblast cell differentiation IMP 2 Publications
hemangioblast cell differentiation IMP MO7-tal1 Xiong et al., 2008
hemopoiesis IDA Hogan et al., 2006
hemopoiesis IGI npas4lDf(Chr13:lycat)m39 (INDO) Liao et al., 1998
hemopoiesis IMP 3 Publications
hemopoiesis IMP MO2-tal1, MO1-tal1 Dooley et al., 2005
lateral mesoderm development IMP MO4-tal1 Rowlinson et al., 2010
multicellular organism development IEA UniProtKB-KW:KW-0217 ZFIN Electronic Annotation
myeloid cell differentiation IEP Juarez et al., 2005
nucleate erythrocyte development IMP MO7-tal1 Qian et al., 2007
nucleate erythrocyte development IMP MO8-tal1 Qian et al., 2007
positive regulation of endothelial cell differentiation IGI npas4lDf(Chr13:lycat)m39 (INDO) Liao et al., 1998
positive regulation of endothelial cell differentiation IMP Gering et al., 1998
primitive hemopoiesis IDA 2 Publications
primitive hemopoiesis IMP 3 Publications
stem cell population maintenance IMP MO7-tal1 Zhen et al., 2013
thyroid gland development IMP MO4-tal1 Alt et al., 2006
vasculogenesis IDA Gering et al., 1998
vasculogenesis IMP Liao et al., 1998