ZFIN ID: ZDB-GENE-040625-2
Gene Name: cytochrome P450, family 51
Gene Symbol: cyp51
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function heme binding IEA InterPro:IPR001128 ZFIN Electronic Annotation
heme binding IEA InterPro:IPR002403 ZFIN Electronic Annotation
heme binding IEA InterPro:IPR036396 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR001128 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR002403 ZFIN Electronic Annotation
iron ion binding IEA InterPro:IPR036396 ZFIN Electronic Annotation
metal ion binding IEA UniProtKB-KW:KW-0479 ZFIN Electronic Annotation
monooxygenase activity IBA UniProtKB:Q8GSQ1, MGI:MGI:1096359, UniProtKB:Q2MJ20, UniProtKB:Q9NR63, UniProtKB:Q6V0L0, TAIR:locus:2152292, UniProtKB:F6H9N6, RGD:631379, UniProtKB:Q5CCK3, UniProtKB:Q8L7D5, TAIR:locus:2091571, TAIR:locus:2098802, TAIR:locus:2158961, UniProtKB:Q9PUB4, TAIR:locus:2115220, PANTHER:PTN000669383, UniProtKB:O43174 Gaudet et al., 2010
monooxygenase activity IEA InterPro:IPR002403 ZFIN Electronic Annotation
monooxygenase activity IEA UniProtKB-KW:KW-0503 ZFIN Electronic Annotation
oxidoreductase activity IBA UniProtKB:Q8GSQ1, PANTHER:PTN001209376, TAIR:locus:2098802, UniProtKB:Q5CCK1, TAIR:locus:2152292, UniProtKB:Q5CCK3, UniProtKB:Q2RAP4 Gaudet et al., 2010
oxidoreductase activity IEA UniProtKB-KW:KW-0560 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR001128 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR002403 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR017972 ZFIN Electronic Annotation
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA InterPro:IPR036396 ZFIN Electronic Annotation
sterol 14-demethylase activity IDA Morrison et al., 2014
Cellular Component endoplasmic reticulum IEA UniProtKB-KW:KW-0256 ZFIN Electronic Annotation
endoplasmic reticulum membrane IEA UniProtKB-SubCell:SL-0097 UniProt-GOA
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
Biological Process cholesterol biosynthetic process IEA UniProtKB-KW:KW-0152 ZFIN Electronic Annotation
cholesterol metabolic process IEA UniProtKB-KW:KW-0153 ZFIN Electronic Annotation
lipid metabolic process IEA UniProtKB-KW:KW-0443 ZFIN Electronic Annotation
oxidation-reduction process IBA TAIR:locus:2040939, PANTHER:PTN001209376, TAIR:locus:2040929, TAIR:locus:2098802, UniProtKB:Q9NR63, UniProtKB:Q6V0L0, TAIR:locus:2094058 Gaudet et al., 2010
oxidation-reduction process IEA InterPro:IPR001128 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR002403 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR017972 ZFIN Electronic Annotation
oxidation-reduction process IEA InterPro:IPR036396 ZFIN Electronic Annotation
oxidation-reduction process IEA UniProtKB-KW:KW-0560 ZFIN Electronic Annotation
response to yeast IDA Wang et al., 2013
steroid biosynthetic process IEA UniProtKB-KW:KW-0752 ZFIN Electronic Annotation
steroid metabolic process IEA UniProtKB-KW:KW-0753 ZFIN Electronic Annotation
sterol biosynthetic process IEA UniProtKB-KW:KW-0756 ZFIN Electronic Annotation
sterol metabolic process IBA PANTHER:PTN001209376, UniProtKB:P9WPP9, TAIR:locus:2027312 Gaudet et al., 2010