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General Information
ZIRC
ZFIN ID: ZDB-GENE-040426-2741
Gene Name: cyclin-dependent kinase 2
Gene Symbol: cdk2
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function ATP binding IEA InterPro:IPR000719 ZFIN Electronic Annotation
ATP binding IEA InterPro:IPR017441 ZFIN Electronic Annotation
ATP binding IEA UniProtKB-KW:KW-0067 ZFIN Electronic Annotation
cyclin binding IBA PANTHER:PTN000623979 Gaudet et al., 2010
cyclin binding IBA RGD:70486, MGI:MGI:104772, PANTHER:PTN000623979, UniProtKB:P24941 Gaudet et al., 2010
cyclin-dependent protein serine/threonine kinase activity IBA PANTHER:PTN000623091 Gaudet et al., 2010
cyclin-dependent protein serine/threonine kinase activity IBA dictyBase:DDB_G0272813, MGI:MGI:104772, SGD:S000005963, SGD:S000001622, RGD:70514, FB:FBgn0263237, FB:FBgn0004106, TAIR:locus:2011761, UniProtKB:Q00534, PomBase:SPAC2F3.15, MGI:MGI:88351, RGD:2319, FB:FBgn0019949, FB:FBgn0013762, PomBase:SPAC23H4.17c, MGI:MGI:88357, WB:WBGene00000405, UniProtKB:O94921, SGD:S000000364, SGD:S000005952, UniProtKB:P50750, UniProtKB:P11802, UniProtKB:Q8IJQ1, UniProtKB:P61075, SGD:S000006365, PomBase:SPBC11B10.09, RGD:621120, FB:FBgn0005640, RGD:70486, PomBase:SPBC32H8.10, UniProtKB:P06493, PomBase:SPBC19F8.07, UniProtKB:C9K505, dictyBase:DDB_G0288677, UniProtKB:P24941, PANTHER:PTN000623091, RGD:621124 Gaudet et al., 2010
kinase activity IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
nucleotide binding IEA UniProtKB-KW:KW-0547 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein kinase activity IEA InterPro:IPR008271 ZFIN Electronic Annotation
protein serine/threonine kinase activity IEA UniProtKB-KW:KW-0723 ZFIN Electronic Annotation
transferase activity IEA UniProtKB-KW:KW-0808 ZFIN Electronic Annotation
Cellular Component cyclin-dependent protein kinase holoenzyme complex IBA PANTHER:PTN000623979 Gaudet et al., 2010
cyclin-dependent protein kinase holoenzyme complex IBA PomBase:SPBC11B10.09, SGD:S000000364, MGI:MGI:104772, PANTHER:PTN000623979, UniProtKB:P24941 Gaudet et al., 2010
cytoplasm IBA PANTHER:PTN000623979 Gaudet et al., 2010
cytoplasm IBA PomBase:SPBC11B10.09, SGD:S000000364, PANTHER:PTN000623979, TAIR:locus:2099478, UniProtKB:P24941 Gaudet et al., 2010
nucleus IBA PANTHER:PTN000623091 Gaudet et al., 2010
nucleus IBA TAIR:locus:2008595, UniProtKB:P49336, RGD:70514, MGI:MGI:101765, TAIR:locus:2194045, UniProtKB:Q8W4P1, UniProtKB:Q92772, UniProtKB:P21127, MGI:MGI:88353, MGI:MGI:88357, UniProtKB:O94921, SGD:S000005952, RGD:1359638, UniProtKB:O76039, UniProtKB:Q8IJQ1, UniProtKB:P61075, TAIR:locus:2033349, SGD:S000006365, TAIR:locus:2080290, RGD:621120, RGD:70486, FB:FBgn0015618, UniProtKB:P79432, TAIR:locus:2158554, dictyBase:DDB_G0288677, RGD:621124, MGI:MGI:104772, UniProtKB:Q9UQ88, SGD:S000001622, FB:FBgn0263237, TAIR:locus:2084086, UniProtKB:Q9NYV4, RGD:619874, UniProtKB:Q00535, MGI:MGI:102956, UniProtKB:Q00534, PomBase:SPAC2F3.15, TAIR:locus:2027819, RGD:2319, UniProtKB:Q8RWN3, FB:FBgn0019949, dictyBase:DDB_G0267442, WB:WBGene00000405, RGD:1305435, SGD:S000000364, SGD:S000002266, UniProtKB:P11802, UniProtKB:P50613, PomBase:SPBC11B10.09, PomBase:SPBC32H8.10, UniProtKB:P06493, MGI:MGI:1328368, UniProtKB:Q8IDW1, TAIR:locus:2099478, MGI:MGI:894318, UniProtKB:P24941, PANTHER:PTN000623091, TAIR:locus:2119961 Gaudet et al., 2010
Biological Process G1/S transition of mitotic cell cycle IBA PANTHER:PTN000623979 Gaudet et al., 2010
G1/S transition of mitotic cell cycle IBA PomBase:SPBC11B10.09, MGI:MGI:104772, PANTHER:PTN000623979 Gaudet et al., 2010
multicellular organism development IBA PANTHER:PTN000623979 Gaudet et al., 2010
phosphorylation IEA UniProtKB-KW:KW-0418 ZFIN Electronic Annotation
positive regulation of cell population proliferation IBA MGI:MGI:104772, PANTHER:PTN000623979, TAIR:locus:2099478, UniProtKB:P24941 Gaudet et al., 2010
positive regulation of cell population proliferation IBA PANTHER:PTN000623979 Gaudet et al., 2010
protein phosphorylation IBA dictyBase:DDB_G0272813, MGI:MGI:104772, UniProtKB:Q9UQ88, SGD:S000005963, SGD:S000001865, SGD:S000001622, RGD:70514, FB:FBgn0263237, SGD:S000005488, FB:FBgn0004106, UniProtKB:Q00534, MGI:MGI:101765, UniProtKB:P21127, MGI:MGI:88351, dictyBase:DDB_G0267442, FB:FBgn0013762, WB:WBGene00000407, WB:WBGene00000405, MGI:MGI:88357, SGD:S000005952, UniProtKB:P50750, UniProtKB:P11802, SGD:S000006365, FB:FBgn0005640, FB:FBgn0015618, UniProtKB:P06493, dictyBase:DDB_G0288677, UniProtKB:P24941, WB:WBGene00019362, PANTHER:PTN000623091, RGD:621124, TAIR:locus:2119961, FB:FBgn0013435 Gaudet et al., 2010
protein phosphorylation IEA InterPro:IPR000719 ZFIN Electronic Annotation
protein phosphorylation IEA InterPro:IPR008271 ZFIN Electronic Annotation
regulation of G2/M transition of mitotic cell cycle IBA PANTHER:PTN000623979 Gaudet et al., 2010
regulation of G2/M transition of mitotic cell cycle IBA PomBase:SPBC11B10.09, PANTHER:PTN000623979 Gaudet et al., 2010
regulation of gene expression IBA PANTHER:PTN000623979 Gaudet et al., 2010
response to organic substance IBA PANTHER:PTN000623979 Gaudet et al., 2010
signal transduction IBA PANTHER:PTN000623979 Gaudet et al., 2010