ZFIN ID: ZDB-GENE-030131-9505
Gene Name: solute carrier family 12 member 3
Gene Symbol: slc12a3
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function cation:chloride symporter activity IEA InterPro:IPR004842 ZFIN Electronic Annotation
potassium:chloride symporter activity IBA UniProtKB:A0A0B4LGD3, MGI:MGI:103150, PANTHER:PTN000214719, MGI:MGI:1862037, RGD:3685, TAIR:locus:2028170, RGD:620809, UniProtKB:Q9H2X9, WB:WBGene00019205, WB:WBGene00006504, RGD:620811, FB:FBgn0036279, SGD:S000000439, UniProtKB:Q9UHW9, UniProtKB:Q6Z0E2 Gaudet et al., 2010
sodium ion transmembrane transporter activity IBA RGD:3686, MGI:MGI:108114, PANTHER:PTN000930537 Gaudet et al., 2010
sodium:chloride symporter activity IBA MGI:MGI:103150, RGD:3686, RGD:3685, FB:FBgn0036279, PANTHER:PTN000930537, RGD:620809 Gaudet et al., 2010
sodium:potassium:chloride symporter activity IBA MGI:MGI:103150, RGD:3685, FB:FBgn0036279, RGD:620809, PANTHER:PTN000930537 Gaudet et al., 2010
transmembrane transporter activity IEA InterPro:IPR018491 ZFIN Electronic Annotation
Cellular Component apical plasma membrane IBA MGI:MGI:101924, RGD:3686, MGI:MGI:103150, MGI:MGI:108114, PANTHER:PTN000930541, UniProtKB:P55017, RGD:3685, UniProtKB:P55011 Gaudet et al., 2010
integral component of membrane IEA InterPro:IPR004842 ZFIN Electronic Annotation
integral component of membrane IEA UniProtKB-KW:KW-0812 ZFIN Electronic Annotation
membrane IEA InterPro:IPR002948 ZFIN Electronic Annotation
membrane IEA InterPro:IPR004841 ZFIN Electronic Annotation
membrane IEA InterPro:IPR018491 ZFIN Electronic Annotation
membrane IEA UniProtKB-KW:KW-0472 ZFIN Electronic Annotation
Biological Process cell volume homeostasis IBA MGI:MGI:101924, PANTHER:PTN000214719, RGD:1359672, RGD:620809 Gaudet et al., 2010
chloride ion homeostasis IBA MGI:MGI:101924, PANTHER:PTN000214719, UniProtKB:Q9H2X9, UniProtKB:Q6Z0E2 Gaudet et al., 2010
chloride transmembrane transport IBA MGI:MGI:101924, PANTHER:PTN000214719, UniProtKB:Q9H2X9, MGI:MGI:1342283 Gaudet et al., 2010
cloaca development IMP MO1-slc12a3 Abu Seman et al., 2014
ion transport IEA InterPro:IPR002948 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR004842 ZFIN Electronic Annotation
ion transport IEA InterPro:IPR018491 ZFIN Electronic Annotation
potassium ion homeostasis IBA MGI:MGI:101924, PANTHER:PTN000214719, SGD:S000000439, UniProtKB:Q6Z0E2 Gaudet et al., 2010
potassium ion import across plasma membrane IBA PANTHER:PTN000214719, UniProtKB:Q9UHW9 Gaudet et al., 2010
pronephric duct morphogenesis IMP MO1-slc12a3 Abu Seman et al., 2014
sodium ion homeostasis IBA MGI:MGI:101924, PANTHER:PTN000930537 Gaudet et al., 2010
sodium ion transmembrane transport IBA MGI:MGI:101924, RGD:3686, MGI:MGI:108114, PANTHER:PTN000930537 Gaudet et al., 2010
transmembrane transport IEA InterPro:IPR004841 ZFIN Electronic Annotation