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General Information
ZIRC
ZFIN ID: ZDB-GENE-001205-4
Gene Name: cathepsin K
Gene Symbol: ctsk
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function cysteine-type endopeptidase activity IBA UniProtKB:P25774, FB:FBgn0013770, UniProtKB:P07858, RGD:621509, PANTHER:PTN000274640, TAIR:locus:2204873, UniProtKB:Q8IIL0, FB:FBgn0030521, UniProtKB:P43235, UniProtKB:P09668, TAIR:locus:505006093, TAIR:locus:2133402, RGD:2448, MGI:MGI:107285, UniProtKB:P07711, TAIR:locus:2157712, MGI:MGI:107341 Gaudet et al., 2010
cysteine-type peptidase activity IEA InterPro:IPR000668 ZFIN Electronic Annotation
cysteine-type peptidase activity IEA UniProtKB-KW:KW-0788 ZFIN Electronic Annotation
hydrolase activity IEA UniProtKB-KW:KW-0378 ZFIN Electronic Annotation
peptidase activity IEA UniProtKB-KW:KW-0645 ZFIN Electronic Annotation
Cellular Component extracellular space IBA UniProtKB:P25774, UniProtKB:P07858, RGD:621509, PANTHER:PTN000274640, RGD:708479, UniProtKB:Q9UBR2, FB:FBgn0034709, UniProtKB:P43235, UniProtKB:P09668, RGD:2447, MGI:MGI:88564, UniProtKB:P07711, RGD:61810, FB:FBgn0034229 Gaudet et al., 2010
lysosome IBA UniProtKB:P25774, FB:FBgn0013770, UniProtKB:P07858, RGD:2445, RGD:621509, PANTHER:PTN000274640, MGI:MGI:1860262, UniProtKB:Q9UBR2, WB:WBGene00000786, dictyBase:DDB_G0279187, UniProtKB:P09668, MGI:MGI:88561, RGD:2448, RGD:2447, MGI:MGI:88564, UniProtKB:P07711, RGD:61810, MGI:MGI:107341 Gaudet et al., 2010
Biological Process bone development IGI gnptab Flanagan-Steet et al., 2016
cartilage development IGI gnptab Flanagan-Steet et al., 2016
proteolysis IEA InterPro:IPR000668 ZFIN Electronic Annotation
proteolysis IEA UniProtKB-KW:KW-0645 ZFIN Electronic Annotation
proteolysis involved in cellular protein catabolic process IBA UniProtKB:P25774, UniProtKB:P07858, PANTHER:PTN000274640, UniProtKB:P43235, UniProtKB:P07711, MGI:MGI:107341 Gaudet et al., 2010
response to mechanical stimulus IDA Kitamura et al., 2013