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General Information
ZIRC
ZFIN ID: ZDB-GENE-000616-15
Gene Name: forkhead box H1
Gene Symbol: foxh1
GO Details
Ontology Qualifier Term Evidence Inferred From Annotation Extension Reference(s)
Molecular Function DNA binding IEA UniProtKB-KW:KW-0238 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR001766 ZFIN Electronic Annotation
DNA-binding transcription factor activity IEA InterPro:IPR030456 ZFIN Electronic Annotation
DNA-binding transcription factor activity, RNA polymerase II-specific IBA PANTHER:PTN000930906, FB:FBgn0000659, WB:WBGene00004013, RGD:621723, UniProtKB:O00358 Gaudet et al., 2010
DNA-binding transcription factor activity, RNA polymerase II-specific IDA Choi et al., 2007
DNA-binding transcription factor activity, RNA polymerase II-specific IGI MO1-smad2 Choi et al., 2007
DNA-binding transcription factor activity, RNA polymerase II-specific IMP foxh1ty68b/ty68b Choi et al., 2007
DNA-binding transcription repressor activity, RNA polymerase II-specific IDA Chen et al., 2015
RNA polymerase II regulatory region sequence-specific DNA binding IDA Chen et al., 2015
sequence-specific DNA binding IDA Chen et al., 2015
sequence-specific DNA binding IEA InterPro:IPR001766 ZFIN Electronic Annotation
sequence-specific DNA binding IEA InterPro:IPR030456 ZFIN Electronic Annotation
sequence-specific DNA binding IMP foxh1m768/m768 Slagle et al., 2011
SMAD binding IMP foxh1pr1/pr1 Slagle et al., 2011
transcription regulatory region sequence-specific DNA binding IDA Chen et al., 2015
Cellular Component chromatin IDA Chen et al., 2015
nucleus IC sequence-specific DNA binding Choi et al., 2007
nucleus IBA UniProtKB:P55317, MGI:MGI:1349428, MGI:MGI:1347466, UniProtKB:O00358, MGI:MGI:1353569, PANTHER:PTN000930906, FB:FBgn0003430, PomBase:SPBC4C3.12, UniProtKB:Q13461, WB:WBGene00001434, WB:WBGene00003017, WB:WBGene00002601, FB:FBgn0014143, SGD:S000000661, WB:WBGene00004013, FB:FBgn0000659, MGI:MGI:1347477, UniProtKB:Q12948, WB:WBGene00006853, MGI:MGI:1347476, WB:WBGene00001441, SGD:S000001393, MGI:MGI:95546, MGI:MGI:1347472, MGI:MGI:1927549, UniProtKB:Q99958, FB:FBgn0004895, UniProtKB:P58012, RGD:2808, RGD:2807, RGD:2809, PomBase:SPBC32H8.11, UniProtKB:Q9Y261 Gaudet et al., 2010
nucleus IBA PANTHER:PTN001371846 Gaudet et al., 2010
nucleus IEA UniProtKB-KW:KW-0539 ZFIN Electronic Annotation
Biological Process anatomical structure morphogenesis IBA PANTHER:PTN000930906, MGI:MGI:1347476 Gaudet et al., 2010
axial mesoderm morphogenesis IMP foxh1m768/m768 Slagle et al., 2011
axial mesodermal cell fate specification IMP foxh1pr1/pr1 Slagle et al., 2011
blood vessel development IMP foxh1ty68b/ty68b Choi et al., 2007
brain morphogenesis IMP foxh1m768/m768 (AB) Schier et al., 1996
cell differentiation IBA PANTHER:PTN000930906, WB:WBGene00004013 Gaudet et al., 2010
cell migration involved in gastrulation IMP MO1-foxh1 Pei et al., 2007
cell migration involved in gastrulation IMP MO2-foxh1 Pei et al., 2007
cellular response to cytokine stimulus ISS UniProtKB:O75593 GOA et al., 2007
determination of left/right symmetry IMP foxh1ty68b/ty68b 2 Publications
dorsal/ventral pattern formation IMP foxh1ty68b/ty68b Pogoda et al., 2000
embryonic heart tube left/right pattern formation IMP foxh1pr1/pr1 Slagle et al., 2011
embryonic heart tube morphogenesis IMP foxh1ty68b/ty68b Chen et al., 1997
endoderm formation IMP foxh1ty68b/ty68b Pogoda et al., 2000
floor plate development IMP foxh1m768/m768 (AB) Stemple et al., 1996
floor plate formation IMP foxh1ty68b/ty68b Odenthal et al., 2000
heart looping IMP foxh1ty68b/ty68b Chen et al., 1997
hypothalamus development IMP foxh1m768/m768 (AB) Schier et al., 1996
mesendoderm development IGI foxh1pr1/pr1 , eomesa Slagle et al., 2011
mesoderm formation IMP foxh1ty68b/ty68b Pogoda et al., 2000
negative regulation of transcription by RNA polymerase II IDA 2 Publications
negative regulation of transcription by RNA polymerase II IMP foxh1ty68b/ty68b Choi et al., 2007
notochord development IMP foxh1m768/m768 (AB) Stemple et al., 1996
notochord formation IMP foxh1pr1/pr1 Slagle et al., 2011
notochord formation IMP foxh1m768/m768 Slagle et al., 2011
optic placode formation involved in camera-type eye formation IMP foxh1m768/m768 (AB) Stemple et al., 1996
positive regulation of transcription by RNA polymerase II ISS UniProtKB:O75593 GOA et al., 2007
prechordal plate formation IMP foxh1pr1/pr1 Slagle et al., 2011
regulation of BMP signaling pathway involved in heart jogging IMP foxh1pr1/pr1 Lenhart et al., 2013
regulation of BMP signaling pathway involved in heart jogging IMP foxh1ty68b/ty68b Chen et al., 1997
regulation of gene expression IMP foxh1ty68b/ty68b Pogoda et al., 2000
regulation of transcription by RNA polymerase II IBA PANTHER:PTN000930906, FB:FBgn0000659, MGI:MGI:1347477, MGI:MGI:1347472, UniProtKB:O00358, UniProtKB:Q9Y261 Gaudet et al., 2010
regulation of transcription by RNA polymerase II IGI MO1-smad2 Choi et al., 2007
regulation of transcription, DNA-templated IEA InterPro:IPR001766 ZFIN Electronic Annotation
regulation of transcription, DNA-templated IEA InterPro:IPR030456 ZFIN Electronic Annotation
somite rostral/caudal axis specification IMP foxh1pr1/pr1 Slagle et al., 2011
specification of animal organ position IMP foxh1ty68b/ty68b Bisgrove et al., 2000
Spemann organizer formation at the embryonic shield IMP foxh1ty68b/ty68b Pogoda et al., 2000