ZFIN

ZFIN ID: ZDB-TGCONSTRCT-070321-2

ZFIN ID: ZDB-TGCONSTRCT-070321-2

CITATIONS (43 total)

Transgenic Construct Name:	Tg(-1.0Cau.Tuba1:GFP)
Transgenic Construct Symbol:	Tg(-1.0Cau.Tuba1:GFP)

Konar, G.J., Lingan, A.L., Vallone, K.T., Nguyen, T.D., Flickinger, Z.R., Patton, J.G. (2025) Depletion of Polypyrimidine tract binding protein 1 (ptbp1) activates Müller glia-derived proliferation during zebrafish retina regeneration via modulation of the senescence secretome. Experimental Eye Research. :110420110420

Konar, G.J., Vallone, K.T., Nguyen, T.D., Patton, J.G. (2025) Analysis of the senescence secretome during zebrafish retina regeneration. Frontiers in aging. 6:15694221569422

Premraj, S., Sharma, P., Chaudhary, M., Shukla, P., Yadav, K., Desai, O.M., Ramachandran, R. (2025) Regulation of the lncRNA malat1/Egr1 axis by Wnt, Notch, and TGF-β signaling: a key mechanism in retina regeneration. NAR molecular medicine. 2:ugaf024ugaf024

Lee, M.S., Jui, J., Sahu, A., Goldman, D. (2024) Mycb and Mych stimulate Müller glial cell reprogramming and proliferation in the uninjured and injured zebrafish retina. Development (Cambridge, England). 151(14):

Palsamy, K., Chen, J.Y., Skaggs, K., Qadeer, Y., Connors, M., Cutler, N., Richmond, J., Kommidi, V., Poles, A., Affrunti, D., Powell, C., Goldman, D., Parent, J.M. (2023) Microglial depletion after brain injury prolongs inflammation and impairs brain repair, adult neurogenesis and pro-regenerative signaling. Glia. 71(11):2642-2663

Kent, M.R., Kara, N., Patton, J.G. (2021) Inhibition of GABA_A-ρ receptors induces retina regeneration in zebrafish. Neural regeneration research. 16:367-374

Sahu, A., Devi, S., Jui, J., Goldman, D. (2021) Notch signaling via Hey1 and Id2b regulates Müller glia's regenerative response to retinal injury. Glia. 69(12):2882-2898

Didiano, D., Abner, J.J., Hinger, S.A., Flickinger, Z., Kent, M., Clement, M.A., Balaiya, S., Liu, Q., Dai, X., Levine, E.M., Patton, J.G. (2020) Induction of a proliferative response in the zebrafish retina by injection of extracellular vesicles. Experimental Eye Research. 200:108254

Lee, M., Wan, J., Goldman, D. (2020) Tgfb3 collaborates with PP2A and Notch signaling pathways to inhibit retina regeneration. eLIFE. 9:

Sharma, P., Gupta, S., Chaudhary, M., Mitra, S., Chawla, B., Khursheed, M.A., Saran, N.K., Ramachandran, R. (2020) Biphasic Role of Tgf-β Signaling during Müller Glia Reprogramming and Retinal Regeneration in Zebrafish. iScience. 23:100817

Kara, N., Kent, M.R., Didiano, D., Rajaram, K., Zhao, A., Summerbell, E.R., Patton, J.G. (2019) The miR-216a-Dot1l Regulatory Axis Is Necessary and Sufficient for Müller Glia Reprogramming during Retina Regeneration. Cell Reports. 28:2037-2047.e4

Mitra, S., Sharma, P., Kaur, S., Khursheed, M.A., Gupta, S., Chaudhary, M., Kurup, A.J., Ramachandran, R. (2019) Dual regulation of lin28a by Myc is necessary during zebrafish retina regeneration. The Journal of cell biology. 218(2):489-507

Sharma, P., Gupta, S., Chaudhary, M., Mitra, S., Chawla, B., Khursheed, M.A., Ramachandran, R. (2019) Oct4 mediates Müller glia reprogramming and cell cycle exit during retina regeneration in zebrafish. Life science alliance. 2(5):

Yu, S., He, J. (2019) Stochastic cell-cycle entry and cell-state-dependent fate outputs of injury-reactivated tectal radial glia in zebrafish. eLIFE. 8

Zhang, Z., Hou, H., Yu, S., Zhou, C., Zhang, X., Li, N., Zhang, S., Song, K., Lu, Y., Liu, D., Lu, H., Xu, H. (2019) Inflammation-induced mammalian target of rapamycin signaling is essential for retina regeneration. Glia. 68(1):111-127

Elsaeidi, F., Macpherson, P., Mills, E.A., Jui, J., Flannery, J.G., Goldman, D. (2018) Notch suppression collaborates with Ascl1 and Lin28 to unleash a regenerative response in fish retina, but not in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(9):2246-2261

Kaur, S., Gupta, S., Chaudhary, M., Khursheed, M.A., Mitra, S., Kurup, A.J., Ramachandran, R. (2018) let-7 MicroRNA-Mediated Regulation of Shh Signaling and the Gene Regulatory Network Is Essential for Retina Regeneration. Cell Reports. 23:1409-1423

Mitra, S., Sharma, P., Kaur, S., Khursheed, M.A., Gupta, S., Ahuja, R., Kurup, A.J., Chaudhary, M., Ramachandran, R. (2018) Histone Deacetylase-Mediated Müller Glia Reprogramming through Her4.1-Lin28a Axis Is Essential for Retina Regeneration in Zebrafish. iScience. 7:68-84

Wang, J., Fei, F., Berberoglu, M.A., Sun, S., Wang, L., Dong, Z., Wang, X. (2018) Csy4-based vector system enables conditional chimeric gene editing in zebrafish without interrupting embryogenesis. Journal of molecular cell biology. 10(6):586-588

Rao, M.B., Didiano, D., Patton, J.G. (2017) Neurotransmitter-Regulated Regeneration in the Zebrafish Retina. Stem Cell Reports. 8(4):831-842

Wan, J., Goldman, D. (2017) Opposing Actions of Fgf8a on Notch Signaling Distinguish Two Muller Glial Cell Populations that Contribute to Retina Growth and Regeneration. Cell Reports. 19:849-862

Powell, C., Cornblath, E., Elsaeidi, F., Wan, J., Goldman, D. (2016) Zebrafish Müller glia-derived progenitors are multipotent, exhibit proliferative biases and regenerate excess neurons. Scientific Reports. 6:24851

Zhang, S., Mu, Z., He, C., Zhou, M., Liu, D., Zhao, X.F., Goldman, D., Xu, H. (2016) Antiviral Drug Ganciclovir Is a Potent Inhibitor of the Proliferation of Müller Glia-Derived Progenitors During Zebrafish Retinal Regeneration. Investigative ophthalmology & visual science. 57:1991-2000

Lattante, S., de Calbiac, H., Le Ber, I., Brice, A., Ciura, S., Kabashi, E. (2015) Sqstm1 knock-down causes a locomotor phenotype ameliorated by rapamycin in a zebrafish model of ALS/FTLD. Human molecular genetics. 24(6):1682-90

MacDonald, R.B., Randlett, O., Oswald, J., Yoshimatsu, T., Franze, K., Harris, W.A. (2015) Müller glia provide essential tensile strength to the developing retina. The Journal of cell biology. 210:1075-83

Powell, C., Cornblath, E., Goldman, D. (2014) Zinc-binding Domain-dependent, Deaminase-independent Actions of Apolipoprotein B mRNA-editing Enzyme, Catalytic Polypeptide 2 (Apobec2), Mediate Its Effect on Zebrafish Retina Regeneration. The Journal of biological chemistry. 289(42):28924-41

Rajaram, K., Summerbell, E.R., Patton, J.G. (2014) Technical brief: Constant intense light exposure to lesion and initiate regeneration in normally pigmented zebrafish. Molecular Vision. 20:1075-84

Skaggs, K., Goldman, D., Parent, J.M. (2014) Excitotoxic brain injury in adult zebrafish stimulates neurogenesis and long-distance neuronal integration. Glia. 62(12):2061-79

Wan, J., Zhao, X.F., Vojtek, A., Goldman, D. (2014) Retinal Injury, Growth Factors, and Cytokines Converge on β-Catenin and pStat3 Signaling to Stimulate Retina Regeneration. Cell Reports. 9(1):285-97

Zhao, X.F., Wan, J., Powell, C., Ramachandran, R., Myers, M.G., Goldman, D. (2014) Leptin and IL-6 Family Cytokines Synergize to Stimulate Müller Glia Reprogramming and Retina Regeneration. Cell Reports. 9(1):272-84

Powell, C., Grant, A.R., Cornblath, E., and Goldman, D. (2013) Analysis of DNA methylation reveals a partial reprogramming of the Muller glia genome during retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 110(49):19814-19819

Powell, C., Elsaeidi, F., and Goldman, D. (2012) Injury-Dependent Muller Glia and Ganglion Cell Reprogramming during Tissue Regeneration Requires Apobec2a and Apobec2b. The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(3):1096-1109

Ramachandran, R., Zhao, X.F., and Goldman, D. (2012) Insm1a-mediated gene repression is essential for the formation and differentiation of Müller glia-derived progenitors in the injured retina. Nature cell biology. 14(10):1013-1023

Ramachandran, R., Zhao, X.F., and Goldman, D. (2011) Ascl1a/Dkk/ beta -catenin signaling pathway is necessary and glycogen synthase kinase-3 beta inhibition is sufficient for zebrafish retina regeneration. Proceedings of the National Academy of Sciences of the United States of America. 108(38):15858-63

Ramachandran, R., Fausett, B.V., and Goldman, D. (2010) Ascl1a regulates Müller glia dedifferentiation and retinal regeneration through a Lin-28-dependent, let-7 microRNA signalling pathway. Nature cell biology. 12(11):1101-1107

Ramachandran, R., Reifler, A., Parent, J.M., and Goldman, D. (2010) Conditional gene expression and lineage tracing of tuba1a expressing cells during zebrafish development and retina regeneration. The Journal of comparative neurology. 518(20):4196-4212

Fausett, B.V., Gumerson, J.D., and Goldman, D. (2008) The proneural basic helix-loop-helix gene ascl1a is required for retina regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. 28(5):1109-1117

Kassen, S.C., Thummel, R., Burket, C.T., Campochiaro, L.A., Harding, M.J., and Hyde, D.R. (2008) The Tg(ccnb1:EGFP) transgenic zebrafish line labels proliferating cells during retinal development and regeneration. Molecular Vision. 14:951-963

Fausett, B.V., and Goldman, D. (2006) A role for alpha1 tubulin-expressing Muller glia in regeneration of the injured zebrafish retina. The Journal of neuroscience : the official journal of the Society for Neuroscience. 26(23):6303-6313

Additional Citations (4):

Zebrafish Nomenclature Committee (2015) Nomenclature Data Curation (2015). Nomenclature Committee Submission.

ZFIN Staff (2015) Data Model Change: Sequence Targeting Reagents Removed from Environment. ZFIN Historical Data.

Zebrafish Nomenclature Committee (2003) Nomenclature Data Curation (2003-2010). Nomenclature Committee Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.