ZFIN

ZFIN ID: ZDB-GENE-030131-3161

CITATIONS (36 total)

Gene Name:	Niemann-Pick disease, type C1
Gene Symbol:	npc1

Quelle-Regaldie, A., Gandoy-Fieiras, N., Rodríguez-Villamayor, P., Maceiras, S., Losada, A.P., Folgueira, M., Cabezas-Sáinz, P., Barreiro-Iglesias, A., Villar-López, M., Quiroga-Berdeal, M.I., Sánchez, L., Sobrido, M.J. (2023) Severe neurometabolic phenotype in npc1^-/- zebrafish with a C-terminal mutation. Frontiers in molecular neuroscience. 16:10786341078634

Liang, X., Cao, S., Xie, P., Hu, X., Lin, Y., Liang, J., Zhang, S., Xian, B., Cao, H., Luan, T., Cai, Z. (2021) Three-Dimensional Imaging of Whole-Body Zebrafish Revealed Lipid Disorders Associated with Niemann-Pick Disease Type C1. Analytical chemistry. 93(23):8178-8187

Tseng, W.C., Johnson Escauriza, A.J., Tsai-Morris, C.H., Feldman, B., Dale, R.K., Wassif, C.A., Porter, F.D. (2021) The role of Niemann-Pick type C2 in zebrafish embryonic development. Development (Cambridge, England). 148(7):

Cook, S.R., Bladen, C., Smith, J., Maguire, E., Copner, J., Fenn, G.D., Wager, K., Waller-Evans, H., Lloyd-Evans, E. (2020) Visualisation of cholesterol and ganglioside GM1 in zebrafish models of Niemann-Pick type C disease and Smith-Lemli-Opitz syndrome using light sheet microscopy. Histochemistry and cell biology. 154(5):565-578

Liao, Y., Wei, J., Wang, J., Shi, X., Luo, J., Song, B.L. (2018) The non-canonical NF-κB pathway promotes NPC2 expression and regulates intracellular cholesterol trafficking. Science China. Life sciences. 61(10):1222-1232

Lin, Y., Caia, X., Wang, G., Ouyang, G., Cao, H. (2018) Model construction of Niemann-Pick Type C disease in zebrafish. Biological chemistry. 399(8):903-910

Sánchez, E., Azcona, L.J., Paisán-Ruiz, C. (2018) Pla2g6 Deficiency in Zebrafish Leads to Dopaminergic Cell Death, Axonal Degeneration, Increased β-Synuclein Expression, and Defects in Brain Functions and Pathways. Molecular neurobiology. 55(8):6734-6754

Tseng, W.C., Loeb, H.E., Pei, W., Tsai-Morris, C.H., Xu, L., Cluzeau, C.V., Wassif, C.A., Feldman, B., Burgess, S.M., Pavan, W.J., Porter, F.D. (2018) Modeling Niemann-Pick disease type C1 in zebrafish: a robust platform for in vivo screening of candidate therapeutic compounds.. Disease models & mechanisms. 11(9)

Bayés, À., Collins, M.O., Reig-Viader, R., Gou, G., Goulding, D., Izquierdo, A., Choudhary, J.S., Emes, R.D., Grant, S.G. (2017) Evolution of complexity in the zebrafish synapse proteome. Nature communications. 8:14613

den Broeder, M.J., Moester, M.J.B., Kamstra, J.H., Cenijn, P.H., Davidoiu, V., Kamminga, L.M., Ariese, F., de Boer, J.F., Legler, J. (2017) Altered Adipogenesis in Zebrafish Larvae Following High Fat Diet and Chemical Exposure Is Visualised by Stimulated Raman Scattering Microscopy. International Journal of Molecular Sciences. 18(4)

Chu, B.B., Liao, Y.C., Qi, W., Xie, C., Du, X., Wang, J., Yang, H., Miao, H.H., Li, B.L., Song, B.L. (2015) Cholesterol transport through lysosome-peroxisome membrane contacts. Cell. 161:291-306

Elkon, R., Milon, B., Morrison, L., Shah, M., Vijayakumar, S., Racherla, M., Leitch, C.C., Silipino, L., Hadi, S., Weiss-Gayet, M., Barras, E., Schmid, C.D., Ait-Lounis, A., Barnes, A., Song, Y., Eisenman, D.J., Eliyahu, E., Frolenkov, G.I., Strome, S.E., Durand, B., Zaghloul, N.A., Jones, S.M., Reith, W., Hertzano, R. (2015) RFX transcription factors are essential for hearing in mice. Nature communications. 6:8549

Hsu, C.H., Lin, J.S., Lai, K.P., Li, J.W., Chan, T.F., You, M.S., Tse, W.K., Jiang, Y.J. (2015) A new mib allele with a chromosomal deletion covering foxc1a exhibits anterior somite specification defect.. Scientific Reports. 5:10673

Louwette, S., Régal, L., Wittevrongel, C., Thys, C., Vandeweeghde, G., Decuyper, E., Leemans, P., De Vos, R., Van Geet, C., Jaeken, J., and Freson, K. (2013) NPC1 defect results in abnormal platelet formation and function: studies in Niemann-Pick disease type C1 patients and zebrafish. Human molecular genetics. 22(1):61-73

Schwend, T., Loucks, E.J., Snyder, D., and Ahlgren, S.C. (2011) Requirement of Npc1 and availability of cholesterol for early embryonic cell movements in Zebrafish. Journal of Lipid Research. 52(7):1328-44

van der Meer, D.L., van den Thillart, G.E., Witte, F., de Bakker, M.A., Besser, J., Richardson, M.K., Spaink, H.P., Leito, J.T., and Bagowski, C.P. (2005) Gene expression profiling of the long-term adaptive response to hypoxia in the gills of adult zebrafish. American journal of physiology. Regulatory, integrative and comparative physiology. 286(5):R1512-1519

Woods, I.G., Wilson, C., Friedlander, B., Chang, P., Reyes, D.K., Nix, R., Kelly, P.D., Chu, F., Postlethwait, J.H., and Talbot, W.S. (2005) The zebrafish gene map defines ancestral vertebrate chromosomes. Genome research. 15(9):1307-1314

Additional Citations (19):

ZFIN Staff (2024) Association of Ensembl transcripts with ZFIN genes. Semi-automated Curation.

ZFIN Staff (2023) Automated Curation of UniProt Database Links. Automated Data Submission.

ZFIN Staff (2020) Addition of links from ZFIN to Expression Atlas. Semi-automated Curation.

Zebrafish Nomenclature Committee (2019) Nomenclature Data Curation (2019). Nomenclature Committee Submission.

Zebrafish Nomenclature Committee (2017) Nomenclature Data Curation (2017). Nomenclature Committee Submission.

ZFIN Staff (2017) Curation of PANTHER Gene IDs. Automated Data Submission.

ZFIN Staff (2017) Curation of Alliance of Genome Resources Database Links. Automated Data Submission.

Busch-Nentwich, E., Kettleborough, R., Dooley, C. M., Scahill, C., Sealy, I., White, R., Herd, C., Mehroke, S., Wali, N., Carruthers, S., Hall, A., Collins, J., Gibbons, R., Pusztai, Z., Clark, R., and Stemple, D.L. (2013) Sanger Institute Zebrafish Mutation Project mutant data submission. ZFIN Direct Data Submission.

ZFIN Staff (2013) Semi-automated association of ENSDARG identifiers with ZFIN genes for the ZMP project. Semi-automated Curation.

Gaudet, P., Livstone, M., Thomas, P., The Reference Genome Project (2010) Annotation inferences using phylogenetic trees. Automated Data Submission.

ZFIN Staff (2007) Microarray Expression to Gene Association in ZFIN. Semi-automated Curation.

Ensembl curators, GOA curators (2006) Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara. Manually curated data.

ZFIN Staff (2006) Curation of Ensembl Database Links. Automated Data Submission.

Thisse, B., Thisse, C. (2004) Fast Release Clones: A High Throughput Expression Analysis. ZFIN Direct Data Submission.

ZFIN Staff (2003) Curation of VEGA Database Links. Automated Data Submission.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of UniProt Keywords with GO Terms. Automated Data Submission.

ZFIN Staff (2002) Curation of NCBI Gene Data Via Shared RNA Sequence IDs. Automated Data Submission.

ZFIN Staff (2002) Scientific Curation. Manually curated data.

ZFIN Staff (2002) Gene Ontology Annotation Through Association of InterPro Records with GO Terms. Automated Data Submission.