ZFIN ID: ZDB-GENO-081010-2 |
Genotype: | kcnh6am230/m230 |
---|---|
Background: | Unspecified |
Affected Genomic Region: | kcnh6a |
Current Source: | No data available |
Note:
T to C transversion predicted to change a highly conserved leucine in the S4 domain (L499P). Most homozygotes die at 6-7 dpf. Rarely, homozygous mutants survive to adulthood and are fertile.
(1)
GENOTYPE COMPOSITION
Genomic Feature | Construct | Lab of Origin | Zygosity | Parental Zygosity |
---|---|---|---|---|
m230 | Driever Lab | homozygous | ♀+/- ♂+/- |
FISH UTILIZING kcnh6am230/m230
Fish | Affected Genomic Regions | Phenotype | Gene Expression |
---|---|---|---|
kcnh6am230/m230 | kcnh6a |
5 figures
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text only from Hassel et al., 2008 |
kcnh6am230/m230 + MO3-kcnh6a | kcnh6a | Fig. 3 from Hassel et al., 2008 | |
kcnh6am230/m230 + MO2-mir19b | kcnh6a |
Fig. 6
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