Gene
kcnh6a
- ID
- ZDB-GENE-040702-5
- Name
- potassium voltage-gated channel, subfamily H (eag-related), member 6a
- Symbol
- kcnh6a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 3 Mapping Details/Browsers
- Description
- Exhibits voltage-gated potassium channel activity. Involved in several processes, including heart contraction; membrane repolarization during cardiac muscle cell action potential; and regulation of ventricular cardiac muscle cell membrane repolarization. Predicted to localize to integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; digestive system; gill; immune system; and muscle. Used to study long QT syndrome and short QT syndrome. Orthologous to human KCNH6 (potassium voltage-gated channel subfamily H member 6).
- Genome Resources
- Note
- None
- Comparative Information
- All Expression Data
- 5 figures from 5 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 30 figures from 14 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Type | InterPro ID | Name |
---|---|---|
Domain | IPR000014 | PAS domain |
Domain | IPR000595 | Cyclic nucleotide-binding domain |
Domain | IPR005821 | Ion transport domain |
Family | IPR003938 | Potassium channel, voltage-dependent, EAG/ELK/ERG |
Family | IPR003967 | Potassium channel, voltage-dependent, ERG |
Family | IPR050818 | Voltage-gated potassium channel family H |
Homologous_superfamily | IPR014710 | RmlC-like jelly roll fold |
Homologous_superfamily | IPR018490 | Cyclic nucleotide-binding domain superfamily |
Homologous_superfamily | IPR035965 | PAS domain superfamily |
Domain Details Per Protein
Protein | Length | Cyclic nucleotide-binding domain | Cyclic nucleotide-binding domain superfamily | Ion transport domain | PAS domain | PAS domain superfamily | Potassium channel, voltage-dependent, EAG/ELK/ERG | Potassium channel, voltage-dependent, ERG | RmlC-like jelly roll fold | Voltage-gated potassium channel family H |
---|---|---|---|---|---|---|---|---|---|---|
UniProtKB:A0A8M2BBD6
|
1185 | |||||||||
UniProtKB:A0A8M3AQY1
|
856 | |||||||||
UniProtKB:Q8JH78
|
1186 | |||||||||
UniProtKB:A0A8M2BBB6
|
915 |
Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
---|---|---|---|---|---|
mRNA |
kcnh6a-201
(1)
|
Ensembl | 4,583 nt | ||
mRNA |
kcnh6a-202
(1)
|
Ensembl | 4,931 nt |
Interactions and Pathways
No data available
Plasmids
No data available