| ZFIN ID: ZDB-ALT-160729-5 |
|
MUTATION DETAILS
| DNA/cDNA Change: | T>A (1) |
|---|---|
| Transcript Consequence: | Missense (1) |
| Protein Consequence: | Amino Acid Substitution: Phe>Ile at position 993 (1) |
| AAAATCAGGAGCAAATAAAAAAACTCTCATACAGAAAATGAGCGAGAAAACAGACATGTGACATTAAACATGAAAATATTGAGATTCAGCAGACATTCAAAGAACTTACACTTCAGTCTATATAATGAGAATGTTAATGTGTTTTTGACTTTCGATGGATGTAAATTTAATGTAGTGCACTAAAATAAAATATAAACCTGTGAAATAGCTTAAAATATGTGCTTGAATGATAAATAGCACATGTGTTAATGTTTGTTTTCTAATGCAAAGAATGTTCCTGCACATGTGGCCAAACCACCGTCATAAAAGCAAAAATGTGTGTTAACTGAGAAACATATGATAGTACAAAGTCTGAATGCACTTAAAAAGGCTCACAGTTCTGGGTCGATTGAGTCTCAAGAAGCTCTTCATGTCTCCTCCTGTCATGAGCTCCAGCAGGATGAAGCGTGGCAGGATCTGCAGACTGACGCCAATGCAGCGGACAATGTTCTGATGGCTGA |
| A/T |
| CTTACTGCAGACACACAAGAAAACCCAAGTGAACTACTGACTGGAAGAACGAGTCAGCTTGATTCTCATACATCAAAACATGTCATAACAGTACTCAACCACAATTCTCAGATATGTGACCCTGGACCACAGAACCAGTCAAATTTTGGAAACGTACGAATTATAATTTTGGGATTTGTGTATTGCCTGAAAGTTAAATAAATTTGTTTTCTATTGATGTGTATTTTGTTAGGACAGGACAATATCTGGCCCAAATACAACTATTTGAATATCTGGAAAATACTAAGAAAATCCTGTTTAAACTTGTTTAAATGAAGTTCTCAGCAATGCATGTTACTAATCCAAAAATGAGTTTTGATATATTTATGGTAGGAAATATTACAAAAGGCGACAAAGTGGCTCAGTGCTTGGCACTGTCGCCTCACAGCAAGAAGGTTGCTGTTTCGAGTCCTGGCTAGGTCAGTTGGCATTTCTGTGTGTAGTTTGTATGTTCTCCCTGT |
| (1) |
| Comment | Citation |
|---|---|
| change in the kinase domain of the protein, which is highly conserved ... | Fadeev et al., 2016 |
OTHER dtwc3 PAGES
No links to external sites
GENOTYPES
| Zygosity | Genotype (Background) | Affected Genomic Regions | Parental Zygosity |
|---|---|---|---|
| Homozygous | ltkdtwc3/dtwc3 | ltk | ♀+/- ♂+/- |
| Heterozygous | ltkdtwc3/+ | ltk | Unknown |
| Complex | ednrbatlf802/tlf802 ; ltkdtwc3/+ | ednrba, ltk | |
| ltkj9s1/+ ; ltkdtwc3/+ | ltk | ||
| kitab134/b134 ; ltkdtwc3/+ | kita, ltk | ||
| t32238Tg ; sb1Tg ; ltkdtwc3/+ | ltk | ||
| t32238Tg ; tdl358Et ; ltkdtwc3/+ | ltk |
CITATIONS (2)