Gene

tmprss5

ID

ZDB-GENE-131121-184

Name

transmembrane serine protease 5

Symbol

tmprss5 Nomenclature History

Previous Names

si:ch211-247l8.7 (1)

Type

protein_coding_gene

Location

Chr: 15 Mapping Details/Browsers

Description

Predicted to enable scavenger receptor activity; serine-type endopeptidase activity; and serine-type exopeptidase activity. Predicted to act upstream of or within proteolysis. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human TMPRSS5 (transmembrane serine protease 5).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UCSC scRNA-seq

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With tmprss5 Human Ortholog

No data available

Associated With tmprss5 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Active_site	IPR018114	Serine proteases, trypsin family, histidine active site
Active_site	IPR033116	Serine proteases, trypsin family, serine active site
Domain	IPR001190	SRCR domain
Domain	IPR001254	Serine proteases, trypsin domain
Domain	IPR015352	Hepsin, SRCR domain
Domain	IPR017448	SRCR-like domain
Family	IPR001314	Peptidase S1A, chymotrypsin family
Homologous_superfamily	IPR009003	Peptidase S1, PA clan
Homologous_superfamily	IPR036772	SRCR-like domain superfamily
Homologous_superfamily	IPR043504	Peptidase S1, PA clan, chymotrypsin-like fold

Domain Details Per Protein

Protein	Length	Hepsin, SRCR domain	Peptidase S1A, chymotrypsin family	Peptidase S1, PA clan	Peptidase S1, PA clan, chymotrypsin-like fold	Serine proteases, trypsin domain	Serine proteases, trypsin family, histidine active site	Serine proteases, trypsin family, serine active site	SRCR domain	SRCR-like domain	SRCR-like domain superfamily
UniProtKB:X1WBX7 InterPro	551
UniProtKB:A0A2R8Q7N1 InterPro	582

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	tmprss5-202 (1) Ensembl	2507 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
ncRNA	tmprss5-002 (1) Ensembl	736 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations