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Gene

dis3

ID
ZDB-GENE-080213-3
Name
DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
Symbol
dis3 Nomenclature History
Previous Names
  • wu:fb08g12
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable 3'-5'-exoribonuclease activity and endonuclease activity. Predicted to be involved in rRNA catabolic process. Predicted to be located in nucleus. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human DIS3 (DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dis3 Human Ortholog
No data available
Associated With dis3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR022966 Ribonuclease II/R, conserved site
Domain IPR001900 Ribonuclease II/R
Domain IPR002716 PIN domain
Domain IPR033770 Exosome complex exonuclease RRP44, S1 domain
Domain IPR033771 Rrp44-like cold shock domain
Domain IPR041505 Dis3-like cold-shock domain 2
Homologous_superfamily IPR012340 Nucleic acid-binding, OB-fold
Homologous_superfamily IPR029060 PIN-like domain superfamily
Domain Details Per Protein
Protein Length Dis3-like cold-shock domain 2 Exosome complex exonuclease RRP44, S1 domain Nucleic acid-binding, OB-fold PIN domain PIN-like domain superfamily Ribonuclease II/R Ribonuclease II/R, conserved site Rrp44-like cold shock domain
UniProtKB:E7FE01 950
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations