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Gene

traf3ip1

ID
ZDB-GENE-040426-1146
Name
TNF receptor-associated factor 3 interacting protein 1
Symbol
traf3ip1 Nomenclature History
Previous Names
  • eli (1)
  • ift54 (1)
  • mipt3 (1)
  • elipsa (1)
  • zgc:63522
Type
protein_coding_gene
Location
Chr: 9 Mapping Details/Browsers
Description
Predicted to enable microtubule binding activity. Involved in regulation of microtubule cytoskeleton organization. Acts upstream of or within several processes, including animal organ development; cerebrospinal fluid circulation; and regulation of microtubule polymerization. Predicted to be located in cell projection; cytoplasm; and cytoskeleton. Predicted to be part of intraciliary transport particle B. Predicted to be active in axoneme; centrosome; and ciliary basal body. Human ortholog(s) of this gene implicated in Senior-Loken syndrome. Orthologous to human TRAF3IP1 (TRAF3 interacting protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
32 figures from 15 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With traf3ip1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Senior-Loken syndrome 9 616629
Associated With traf3ip1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR040468 TRAF3-interacting protein 1, N-terminal
Domain IPR041476 TRAF3-interacting protein 1, C-terminal domain
Family IPR018799 TRAF3-interacting protein 1
Homologous_superfamily IPR042576 TRAF3-interacting protein 1, N-terminal domain superfamily
Domain Details Per Protein
Protein Length TRAF3-interacting protein 1 TRAF3-interacting protein 1, C-terminal domain TRAF3-interacting protein 1, N-terminal TRAF3-interacting protein 1, N-terminal domain superfamily
UniProtKB:A0A2R8PWH6 637
UniProtKB:B0S7L7 629
UniProtKB:Q6PGZ3 629
UniProtKB:B2BWH3 629
UniProtKB:A0A0R4IR02 644
UniProtKB:E9QHR4 220
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations