Gene

mki67

ID

ZDB-GENE-030131-9771

Name

marker of proliferation Ki-67

Symbol

mki67 Nomenclature History

Previous Names

cb31 (1)
sb:cb31 (1)
si:ch211-250b22.7 (1)
wu:fa11g09
wu:fb57a07
wu:fi14e05

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Human ortholog(s) of this gene implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Is expressed in several structures, including blood; head; pectoral fin bud; pectoral fin musculature; and ventral mesoderm. Orthologous to human MKI67 (marker of proliferation Ki-67).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

6 figures from Thisse et al., 2001

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

cb31 (8 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With mki67 Human Ortholog

No data available

Associated With mki67 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000253	Forkhead-associated (FHA) domain
Domain	IPR029334	Protein phosphatase 1 binding domain
Homologous_superfamily	IPR008984	SMAD/FHA domain superfamily
Repeat	IPR012568	KI67R