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Gene

mki67

ID
ZDB-GENE-030131-9771
Name
marker of proliferation Ki-67
Symbol
mki67 Nomenclature History
Previous Names
  • cb31 (1)
  • sb:cb31 (1)
  • si:ch211-250b22.7 (1)
  • wu:fa11g09
  • wu:fb57a07
  • wu:fi14e05
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to be involved in regulation of chromosome segregation and regulation of mitotic nuclear division. Predicted to be active in chromosome and nucleus. Is expressed in several structures, including blood; head; pectoral fin bud; pectoral fin musculature; and ventral mesoderm. Human ortholog(s) of this gene implicated in Crohn's disease; breast cancer; human immunodeficiency virus infectious disease; and pancreatic cancer. Orthologous to human MKI67 (marker of proliferation Ki-67).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
6 figures from Thisse et al., 2001
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With mki67 Human Ortholog
No data available
Associated With mki67 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000253 Forkhead-associated (FHA) domain
Domain IPR029334 Protein phosphatase 1 binding domain
Homologous_superfamily IPR008984 SMAD/FHA domain superfamily
Repeat IPR012568 KI67R
Domain Details Per Protein
Protein Length Forkhead-associated (FHA) domain KI67R Protein phosphatase 1 binding domain SMAD/FHA domain superfamily
UniProtKB:E7F3N4 2057
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations