Transgenic Construct

Tg(sox10:irf6_R84C,myl7:EGFP)

ID
ZDB-TGCONSTRCT-130911-3
Name
Tg(sox10:irf6_R84C,myl7:EGFP)
Previous Names
  • Tg(sox10:irf6_R84C) (1)
Type
engineered_plasmid
Regulatory Regions
Coding Sequences
[Em λ][Ex λ]
Fpbase:EGFP
Contains Sequences
Note
This construct expresses dominant negative R84C irf6 under the control of the sox10 promoter. Created to model human IRF6 mutations in which arginine 84 plays a crucial role in DNA binding.
Reference: Dougherty et al. (2013)
Plasmid Map
None
Genomic Features
That Utilize Tg(sox10:irf6_R84C,myl7:EGFP) Construct
Genomic Feature Affected Genomic Regions
zf394Tg
Transgenics
That Utilize Tg(sox10:irf6_R84C,myl7:EGFP) Construct
Fish Affected Genomic Regions Phenotype Gene Expression
zf394Tg
Fig. 3 with image from Dougherty et al., 2013
Sequence Information
Other Construct Pages
None
Citations