ZFIN ID: ZDB-PERS-960805-21
Akimenko, Marie-Andree
Email: makimen@uottawa.ca
URL: http://www.careg.uottawa.ca/bio_marie_andree_akimenko.htm
Affiliation: Akimenko Lab
Address: Loeb Health Research Institute Ottawa Civic Hospital 725 Parkdale Avenue Ottawa, Ontario, K1Y 4E9 Canada
Country: Canada
Phone: (613) 562 5800 ext 7399
Fax: (613) 562 5486


Cadiz, L., Reed, M., Monis, S., Akimenko, M.A., Jonz, M.G. (2023) Identification of signalling pathways involved in gill regeneration in zebrafish. The Journal of experimental biology. 227(2):
Nicolas, H.A., Hua, K., Quigley, H., Ivare, J., Tesson, F., Akimenko, M.A. (2022) A CRISPR/Cas9 zebrafish lamin A/C mutant model of muscular laminopathy. Developmental Dynamics : an official publication of the American Association of Anatomists. 251(4):645-661
Li, L., Zhang, J., Akimenko, M.A. (2019) Inhibition of mmp13a during zebrafish fin regeneration disrupts fin growth, osteoblasts differentiation and Laminin organization. Developmental Dynamics : an official publication of the American Association of Anatomists. 249(2):187-198
Phan, H.E., Northorp, M., Lalonde, R.L., Ngo, D., Akimenko, M.A. (2019) Differential actinodin1 regulation in embryonic development and adult fin regeneration in Danio rerio. PLoS One. 14:e0216370
McMillan, S.C., Akimenko, M.A. (2018) Scales Radi(i)cally Remodel Sensory Axons and Vasculature. Developmental Cell. 46:253-254
McMillan, S.C., Zhang, J., Phan, H.E., Jeradi, S., Probst, L., Hammerschmidt, M., Akimenko, M.A. (2018) A regulatory pathway involving retinoic acid and calcineurin demarcates and maintains joint cells and osteoblasts in the fin regenerate. Development (Cambridge, England). 145(11)
Lalonde, R.L., Akimenko, M.A. (2018) Effects of fin fold mesenchyme ablation on fin development in zebrafish. PLoS One. 13:e0192500
Lalonde, R.L., Akimenko, M.A. (2018) Contributions of 5'HoxA/D regulation to actinodin evolution and the fin-to-limb transition. The International journal of developmental biology. 62:705-716
Kherdjemil, Y., Lalonde, R.L., Sheth, R., Dumouchel, A., de Martino, G., Pineault, K.M., Wellik, D.M., Stadler, H.S., Akimenko, M.A., Kmita, M. (2016) Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state. Nature. 539(7627):89-92
Lalonde, R.L., Moses, D., Zhang, J., Cornell, N., Ekker, M., Akimenko, M.A. (2016) Differential actinodin1 regulation in zebrafish and mouse appendages. Developmental Biology. 417(1):91-103
Hanwell, D., Hutchinson, S.A., Collymore, C., Bruce, A.E., Louis, R., Ghalami, A., Allison, W.T., Ekker, M., Eames, B.F., Childs, S., Kurrasch, D.M., Gerlai, R., Thiele, T., Scott, I., Ciruna, B., Dowling, J.J., McFarlane, S., Huang, P., Wen, X.Y., Akimenko, M.A., Waskiewicz, A.J., Drapeau, P., Babiuk, L.A., Dragon, D., Smida, A., Buret, A.G., O'Grady, E., Wilson, J., Sowden-Plunkett, L., Tropepe, V. (2016) Restrictions on the Importation of Zebrafish into Canada Associated with Spring Viremia of Carp Virus. Zebrafish. 13 Suppl 1:S153-63
McMillan, S.C., Géraudie, J., Akimenko, M. (2015) Pectoral Fin Breeding Tubercle Clusters: A Method to Determine Zebrafish Sex. Zebrafish. 12(1):121-3
McMillan, S.C., Xu, Z.T., Zhang, J., Teh, C., Korzh, V., Trudeau, V.L., and Akimenko, M.A. (2013) Regeneration of breeding tubercles on zebrafish pectoral fins requires androgens and two waves of revascularization. Development (Cambridge, England). 140(21):4323-4334
Jackson, R., Braubach, O.R., Bilkey, J., Zhang, J., Akimenko, M.A., Fine, A., Croll, R.P., and Jonz, M.G. (2013) Expression of sall4 in taste buds of zebrafish. Developmental Neurobiology. 73(7):543-58
Zhang, J., Jeradi, S., Strähle, U., and Akimenko, M.A. (2012) Laser ablation of the sonic hedgehog-a-expressing cells during fin regeneration affects ray branching morphogenesis. Developmental Biology. 365(2):424-433
Rolland-Lagan, A.G., Paquette, M., Tweedle, V., and Akimenko, M.A. (2012) Morphogen-based simulation model of ray growth and joint patterning during fin development and regeneration. Development (Cambridge, England). 139(6):1188-1197
Huang, L., Szymanska, K., Jensen, V.L., Janecke, A.R., Innes, A.M., Davis, E.E., Frosk, P., Li, C., Willer, J.R., Chodirker, B.N., Greenberg, C.R., McLeod, D.R., Bernier, F.P., Chudley, A.E., Müller, T., Shboul, M., Logan, C.V., Loucks, C.M., Beaulieu, C.L., Bowie, R.V., Bell, S.M., Adkins, J., Zuniga, F.I., Ross, K.D., Wang, J., Ban, M.R., Becker, C., Nürnberg, P., Douglas, S., Craft, C.M., Akimenko, M.A., Hegele, R.A., Ober, C., Utermann, G., Bolz, H.J., Bulman, D.E., Katsanis, N., Blacque, O.E., Doherty, D., Parboosingh, J.S., Leroux, M.R., Johnson, C.A., and Boycott, K.M. (2011) TMEM237 Is Mutated in Individuals with a Joubert Syndrome Related Disorder and Expands the Role of the TMEM Family at the Ciliary Transition Zone. American journal of human genetics. 89(6):713-730
Zhang, J., Wagh, P., Guay, D., Sanchez-Pulido, L., Padhi, B.K., Korzh, V., Andrade-Navarro, M.A., and Akimenko, M.A. (2010) Loss of fish actinotrichia proteins and the fin-to-limb transition. Nature. 466(7303):234-237
Khatib, A.M., Lahlil, R., Scamuffa, N., Akimenko, M.A., Ernest, S., Lomri, A., Lalou, C., Seidah, N.G., Villoutreix, B.O., Calvo, F., and Siegfried, G. (2010) Zebrafish ProVEGF-C Expression, Proteolytic Processing and Inhibitory Effect of Unprocessed ProVEGF-C during Fin Regeneration. PLoS One. 5(7):e11438
Avaron, F., Smith, A., and Akimenko, M.A. (2008) Sonic Hedgehog Signalling in the Developing and Regenerating Fins of Zebrafish. Molecular Biology Intelligence Unit. :93-106
Smith, A., Zhang, J., Guay, D., Quint, E., Johnson, A., and Akimenko, M.A. (2008) Gene expression analysis on sections of zebrafish regenerating fins reveals limitations in the whole-mount in situ hybridization method. Developmental Dynamics : an official publication of the American Association of Anatomists. 237(2):417-425
Murciano, C., Pérez-Claros, J., Smith, A., Avaron, F., Fernández, T.D., Durán, I., Ruiz-Sánchez, J., García, F., Becerra, J., Akimenko, M.A., and Marí-Beffa, M. (2007) Position dependence of hemiray morphogenesis during tail fin regeneration in Danio rerio. Developmental Biology. 312(1):272-283
Smith, A., Avaron, F., Guay, D., Padhi, B.K., and Akimenko, M.A. (2006) Inhibition of BMP signaling during zebrafish fin regeneration disrupts fin growth and scleroblast differentiation and function. Developmental Biology. 299(2):438-454
Padhi, B.K., Akimenko, M.A., and Ekker, M. (2006) Independent expansion of the keratin gene family in teleostean fish and mammals: An insight from phylogenetic analysis and radiation hybrid mapping of keratin genes in zebrafish. Gene. 368:37-45
Avaron, F., Hoffman, L., Guay, D., and Akimenko, M.A. (2006) Characterization of two new zebrafish members of the hedgehog family: Atypical expression of a zebrafish indian hedgehog gene in skeletal elements of both endochondral and dermal origins. Developmental Dynamics : an official publication of the American Association of Anatomists. 235(2):478-489
Padhi, B.K., Joly, L., Tellis, P., Smith, A., Nanjappa, P., Chevrette, M., Ekker, M., and Akimenko, M.A. (2004) Screen for genes differentially expressed during regeneration of the zebrafish caudal fin. Developmental Dynamics : an official publication of the American Association of Anatomists. 231(3):527-541
Sire, J.Y., and Akimenko, M.A. (2004) Scale development in fish: a review, with description of sonic hedgehog (shh) expression in the zebrafish (Danio rerio). The International journal of developmental biology. 48(2-3):233-246
Schoft, V.K., Beauvais, A.J., Lang, C., Gajewski, A., Prufert, K., Winkler, C., Akimenko, M.-A., Paulin-Levasseur, M., and Krohne, G. (2003) The lamina-associated polypeptide 2 (LAP2) isoforms {beta}, {gamma} and {omega} of zebrafish: developmental expression and behavior during the cell cycle. Journal of Cell Science. 116(12):2505-2517
Akimenko, M.-A., Marí-Beffa, M., Becerra, J., and Géraudie, J. (2003) Old questions, new tools, and some answers to the mystery of fin regeneration. Developmental Dynamics : an official publication of the American Association of Anatomists. 226(2):190-201
Murciano,C., Fernández, T.D., Durán, I., Maseda, D., Riuz-Sánchez, J., Becerra, J., Akimenko, M.-A., and Marí-Beffa, M. (2002) Ray-interray interactions during fin regeneration of Danio rerio. Developmental Biology. 252(2):4-224
Quint, E., Smith, A., Avaron, F., Laforest, L., Miles, J., Gaffield, W., and Akimenko, M.-A. (2002) Bone patterning is altered in the regenerating zebrafish caudal fin after ectopic expression of sonic hedgehog and bmp2b or exposure to cyclopamine. Proceedings of the National Academy of Sciences of the United States of America. 99(13):8713-8718
Hoffman, L., Miles, J., Avaron, F., Laforest, L., and Akimenko, M.-A. (2002) Exogenous retinoic acid induces a stage-specific, transient and progressive extension of Sonic hedgehog expression across the pectoral fin bud of zebrafish. The International journal of developmental biology. 46(7):949-956
Poleo, G., Brown, C.W., Laforest, L., and Akimenko, M.A. (2001) Cell proliferation and movement during early fin regeneration in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 221(4):380-390
Cadieux, B., James, S., Fryer, J.N., Ekker, M., Akimenko, M.-A., and Bennett, H.P.J. (2001) Characterization and tissue distribution of zebrafish granulins: Growth factors with possible roles in development and fin regeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(5):A746
Boué-Grabot, E., Akimenko, M.A., and Séguéla, P. (2000) Unique functional properties of a sensory neuronal P2X ATP-gated channel from zebrafish. Journal of neurochemistry. 75(4):1600-1607
Boue-Grabot, E., Akimenko, M.-A., and Seguela, P. (2000) Unique functional properties of a novel developmentally-regulated neuronal P2X ATP-gated channel from zebrafish. The European journal of neuroscience. 12:452
Wang, J.M., Prefontaine, G.G., Lemieux, M.E., Pope, L., Akimenko, M.A., and Hache, R.J. (1999) Developmental effects of ectopic expression of the glucocorticoid receptor DNA binding domain are alleviated by an amino acid substitution that interferes with homeodomain binding. Molecular and cellular biology. 19(10):7106-7122
Monnot, M.J., Babin, P.J., Poleo, G., Andre, M., Laforest, L., Ballagny, C., and Akimenko, M.A. (1999) Epidermal expression of apolipoprotein E gene during fin and scale development and fin regeneration in zebrafish. Developmental Dynamics : an official publication of the American Association of Anatomists. 214(3):207-215
Martin, C.C., Laforest, L., Akimenko, M.-A., and Ekker, M. (1999) A role for DNA methylation in gastrulation and somite patterning. Developmental Biology. 206:189-205
Laforest, L., Brown, C.W., Poleo, G., Géraudie, J., Tada, M., Ekker, M., and Akimenko, M.-A. (1998) Involvement of the Sonic hedgehog, patched 1, and bmp2 genes in patterning of the zebrafish dermal fin rays. Development (Cambridge, England). 125:4175-4184
Akimenko, M.-A. and Cold Spring Harbor Laboratory (1998) Abstracts of papers presented at the 1998 meeting on zebrafish development & genetics, April 29-May 3, 1998. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory. :318 p
Ekker, M., Akimenko, M.-A., Allende, M.L., Smith, R., Drouin, G., Langille, R.M., Weinberg, E.S., and Westerfield, M. (1997) Relationships among msx gene structure and function in zebrafish and other vertebrates. Mol. Biol. Evol.. 14:1008-1022
Babin, P.J., Thisse, C., Durliat, M., Andre, M., Akimenko, M.-A., and Thisse, B. (1997) Both apolipoprotein E and A-I genes are present in a nonmammalian vertebrate and are highly expressed during embryonic development. Proceedings of the National Academy of Sciences of the United States of America. 94(16):8622-8627
Ellies, D.L., Langille, R.M., Martin, C.C., Akimenko, M.A., and Ekker, M. (1997) Specific craniofacial cartilage dysmorphogenesis coincides with a loss of dlx gene expression in retinoic acid-treated zebrafish embryos. Mechanisms of Development. 61(1-2):23-36
Akimenko, M.A. and Ekker, M. (1995) Anterior duplication of the Sonic hedgehog expression pattern in the pectoral fin buds of zebrafish treated with retinoic acid. Developmental Biology. 170:243-247
Akimenko, M.A., Johnson, S.L., Westerfield, M., and Ekker, M. (1995) Differential induction of four msx homeobox genes during fin development and regeneration in zebrafish. Development (Cambridge, England). 121:347-357
Akimenko, M.A., Ekker, M., Wegner, J., Lin, W., and Westerfield, M. (1994) Combinatorial expression of three zebrafish genes related to distal-less: part of a homeobox gene code for the head. The Journal of neuroscience : the official journal of the Society for Neuroscience. 14:3475-3486
Westerfield, M., Akimenko, M.A., Ekker, M., and Püschel, A. (1993) Eyes, ears and homeobox genes in zebrafish embryos. In Molecular Basis of Morphogenesis, M. Bernfield, ed., New York, NY: John Wiley & Sons, Wiley-Liss Division. :67-75
Ekker, M., Wegner, J., Akimenko, M.A., and Westerfield, M. (1992) Coordinate embryonic expression of three zebrafish engrailed genes. Development (Cambridge, England). 116:1001-1010
Ekker, M., Akimenko, M.A., BreMiller, R., and Westerfield, M. (1992) Regional expression of three homeobox transcripts in the inner ear of zebrafish embryos. Neuron. 9:27-35
Westerfield, M., Wegner, J., Akimenko, M., Ekker, M., Eisen, J., and Halpern, M. (1991) A role for engrailed gene in zebrafish muscle patterning. Soc. Neurosci. Abstr.. 17:761
Ekker, M., Akimenko, M.A., BreMiller, R., and Westerfield, M. (1991) Characterization of four homeobox genes expressed in zebrafish neural crest. Soc. Neurosci. Abstr.. 17:924
Ekker, M. and Akimenko, M.A. (1991) Embryology and genetics of the zebrafish, Brachydanio rerio. Int. J. Bio. Med.. 7:553-560
Akimenko, M.A., Ekker, M., and Westerfield, M. (1990) Characterization of three zebrafish genes related to Hox-7. In Developmental Patterning of the Vertebrate Limb, J.R. Hinchliffe, J. Hurle and D. Summerbell, eds., New York: Plenum Press. :61-63