ZFIN ID: ZDB-PERS-050628-5
Gestri, Gaia
Email: g.gestri@ucl.ac.uk
Affiliation: Steve Wilson Lab
Address: Department of Anatomy and Developmental Biology University College London Gower Street London, WC1E 6BT United Kingdom
Country: United Kingdom
Phone: 44-207-6793330


Powell, G.T., Faro, A., Zhao, Y., Stickney, H., Novellasdemunt, L., Henriques, P., Gestri, G., Redhouse White, E., Ren, J., Lu, W., Young, R.M., Hawkins, T.A., Cavodeassi, F., Schwarz, Q., Dreosti, E., Raible, D.W., Li, V.S.W., Wright, G.J., Jones, E.Y., Wilson, S.W. (2024) Cachd1 interacts with Wnt receptors and regulates neuronal asymmetry in the zebrafish brain. Science (New York, N.Y.). 384:573579573-579
Hernández-Bejarano, M., Gestri, G., Monfries, C., Tucker, L., Dragomir, E.I., Bianco, I.H., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2022) Foxd1-dependent induction of a temporal retinal character is required for visual function. Development (Cambridge, England). 149(24):
Lubin, A., Otterstrom, J., Hoade, Y., Bjedov, I., Stead, E., Whelan, M., Gestri, G., Paran, Y., Payne, E. (2021) A versatile, automated and high-throughput drug screening platform for zebrafish embryos. Biology Open. 10(9):
Kroll, F., Powell, G.T., Ghosh, M., Gestri, G., Antinucci, P., Hearn, T.J., Tunbak, H., Lim, S., Dennis, H.W., Fernandez, J.M., Whitmore, D., Dreosti, E., Wilson, S.W., Hoffman, E.J., Rihel, J. (2021) A simple and effective F0 knockout method for rapid screening of behaviour and other complex phenotypes. eLIFE. 10:
Wycliffe, R., Plaisancie, J., Leaman, S., Santis, O., Tucker, L., Cavieres, D., Fernandez, M., Weiss-Garrido, C., Sobarzo, C., Gestri, G., Valdivia, L.E. (2020) Developmental delay during eye morphogenesis underlies optic cup and neurogenesis defects in mab21l2u517 zebrafish mutants. The International journal of developmental biology. 65(4-5-6):289-299
Young, R.M., Hawkins, T.A., Cavodeassi, F., Stickney, H.L., Schwarz, Q., Lawrence, L.M., Wierzbicki, C., Cheng, B.Y., Luo, J., Ambrosio, E.M., Klosner, A., Sealy, I.M., Rowell, J., Trivedi, C.A., Bianco, I.H., Allende, M.L., Busch-Nentwich, E.M., Gestri, G., Wilson, S.W. (2019) Compensatory growth renders Tcf7l1a dispensable for eye formation despite its requirement in eye field specification. eLIFE. 8:
Turner, K.J., Hoyle, J., Valdivia, L.E., Cerveny, K.L., Hart, W., Mangoli, M., Geisler, R., Rees, M., Houart, C., Poole, R.J., Wilson, S.W., Gestri, G. (2019) Abrogation of Stem Loop Binding Protein (Slbp) function leads to a failure of cells to transition from proliferation to differentiation, retinal coloboma and midline axon guidance deficits. PLoS One. 14:e0211073
Gestri, G., Bazin-Lopez, N., Scholes, C., Wilson, S.W. (2018) Cell Behaviors during Closure of the Choroid Fissure in the Developing Eye. Frontiers in Cellular Neuroscience. 12:42
Valdivia, L.E., Lamb, D.B., Horner, W., Wierzbicki, C., Tafessu, A., Williams, A.M., Gestri, G., Krasnow, A.M., Vleeshouwer-Neumann, T.S., Givens, M., Young, R.M., Lawrence, L.M., Stickney, H.L., Hawkins, T.A., Schwarz, Q.P., Cavodeassi, F., Wilson, S.W., Cerveny, K.L. (2016) Antagonism between Gdf6a and retinoic acid pathways controls timing of retinal neurogenesis and growth of the eye in zebrafish. Development (Cambridge, England). 143(7):1087-98
Hernández-Bejarano, M., Gestri, G., Spawls, L., Nieto-López, F., Picker, A., Tada, M., Brand, M., Bovolenta, P., Wilson, S.W., Cavodeassi, F. (2015) Opposing Shh and Fgf signals initiate nasotemporal patterning of the retina. Development (Cambridge, England). 142(22):3933-42
Miesfeld, J.B., Gestri, G., Clark, B.S., Flinn, M.A., Poole, R.J., Bader, J.R., Besharse, J.C., Wilson, S.W., Link, B.A. (2015) Yap and Taz regulate retinal pigment epithelial cell fate. Development (Cambridge, England). 142(17):3021-32
Fantin, A., Lampropoulou, A., Gestri, G., Raimondi, C., Senatore, V., Zachary, I., Ruhrberg, C. (2015) NRP1 Regulates CDC42 Activation to Promote Filopodia Formation in Endothelial Tip Cells. Cell Reports. 11(10):1577-90
Bazin-Lopez, N., Valdivia, L.E., Wilson, S.W., Gestri, G. (2015) Watching eyes take shape. Current opinion in genetics & development. 32C:73-79
Hüsken, U., Stickney, H.L., Gestri, G., Bianco, I.H., Faro, A., Young, R.M., Roussigne, M., Hawkins, T.A., Beretta, C.A., Brinkmann, I., Paolini, A., Jacinto, R., Albadri, S., Dreosti, E., Tsalavouta, M., Schwarz, Q., Cavodeassi, F., Barth, A.K., Wen, L., Zhang, B., Blader, P., Yaksi, E., Poggi, L., Zigman, M., Lin, S., Wilson, S.W., Carl, M. (2014) Tcf7l2 Is Required for Left-Right Asymmetric Differentiation of Habenular Neurons. Current biology : CB. 24(19):2217-27
Cardozo, M.J., Sánchez-Arrones, L., Sandonis, A., Sánchez-Camacho, C., Gestri, G., Wilson, S.W., Guerrero, I., Bovolenta, P. (2014) Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Nature communications. 5:4272
Andreazzoli, M., Gestri, G., Landi, E., D'Orsi, B., Barilari, M., Iervolino, A., Vitiello, M., Wilson, S.W., and Dente, L. (2012) Kidins220/ARMS interacts with Pdzrn3, a protein containing multiple binding domains. Biochimie. 94(9):2054-2057
Gestri, G., Link, B.A., and Neuhauss, S.C. (2012) The visual system of zebrafish and its use to model human ocular diseases. Developmental Neurobiology. 72(3):302-327
Chiavacci, E., Dolfi, L., Verduci, L., Meghini, F., Gestri, G., Evangelista, A.M., Wilson, S.W., Cremisi, F., and Pitto, L. (2012) MicroRNA 218 Mediates the Effects of Tbx5a Over-Expression on Zebrafish Heart Development. PLoS One. 7(11):e50536
Lupo, G., Gestri, G., O'Brien, M., Denton, R.M., Chandraratna, R.A., Ley, S.V., Harris, W.A., and Wilson, S.W. (2011) Retinoic acid receptor signaling regulates choroid fissure closure through independent mechanisms in the ventral optic cup and periocular mesenchyme. Proceedings of the National Academy of Sciences of the United States of America. 108(21):8698-8703
Dente, L., Gestri, G., Tsang, M., Kudoh, T., Wilson, S.W., Dawid, I.B., and Andreazzoli, M. (2011) Cloning and developmental expression of zebrafish pdzrn3. The International journal of developmental biology. 55(10-12):989-993
Tschopp, M., Takamiya, M., Cerveny, K.L., Gestri, G., Biehlmaier, O., Wilson, S.W., Strähle, U., and Neuhauss, S.C. (2010) Funduscopy in adult zebrafish and its application to isolate mutant strains with ocular defects. PLoS One. 5(11):e15427
Fantin, A., Vieira, J.M., Gestri, G., Denti, L., Schwarz, Q., Prykhozhij, S., Peri, F., Wilson, S.W., and Ruhrberg, C. (2010) Tissue macrophages act as cellular chaperones for vascular anastomosis downstream of VEGF-mediated endothelial tip cell induction. Blood. 116(5):829-840
Gestri, G., Osborne, R.J., Wyatt, A.W., Gerrelli, D., Gribble, S., Stewart, H., Fryer, A., Bunyan, D.J., Prescott, K., Collin, J.R., Fitzgerald, T., Robinson, D., Carter, N.P., Wilson, S.W., and Ragge, N.K. (2009) Reduced TFAP2A function causes variable optic fissure closure and retinal defects and sensitizes eye development to mutations in other morphogenetic regulators. Human genetics. 126(6):791-803
McMahon, C., Gestri, G., Wilson, S.W., and Link, B.A. (2009) Lmx1b is essential for survival of periocular mesenchymal cells and influences Fgf-mediated retinal patterning in zebrafish. Developmental Biology. 332(2):287-298
Gestri, G., Carl, M., Appolloni, I., Wilson, S.W., Barsacchi, G., and Andreazzoli, M. (2005) Six3 functions in anterior neural plate specification by promoting cell proliferation and inhibiting Bmp4 expression. Development (Cambridge, England). 132(10):2401-2413