ZFIN ID: ZDB-MRPHLNO-070719-1
Morpholino Name: MO5-tp53
Target: tp53 (1)
Sequence:
5' - GACCTCCTCTCCACTAAACTACGAT - 3'
   
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  (Although ZFIN verifies reagent sequence data, we recommend that you conduct independent sequence analysis before ordering any reagent.)
TARGET LOCATIONS
No data available
CONSTRUCTS WITH SEQUENCES FROM MO5-tp53 No data available
GENE EXPRESSION
Gene expression in Wild Types + MO5-tp53
Expressed Gene Anatomy Figures
sod1 Fig. 1 from Chen et al., 2011
PHENOTYPE
Phenotype resulting from MO5-tp53
No data available

Phenotype of all Fish created by or utilizing MO5-tp53
Phenotype Fish Conditions Figures
retinal ganglion cell decreased amount, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 8 with image from Yao et al., 2010
pharyngeal arch 3-7 decreased size, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
somite cuboid, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 12 with image from Yao et al., 2010
somite border deformed, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with imageFig. 11 with image from Yao et al., 2010
skeletal muscle cell disorganized, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 12 with image from Yao et al., 2010
retina disorganized, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 10 with image from Yao et al., 2010
vertical myoseptum decreased length, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 12 with image from Yao et al., 2010
retinal neural layer morphology, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 8 with image from Yao et al., 2010
retina development in camera-type eye disrupted, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 10 with image from Yao et al., 2010
extension decreased length, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
somite U-shaped, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with imageFig. 11 with imageFig. 12 with image from Yao et al., 2010
whole organism anterior-posterior axis curved ventral, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
somitogenesis disrupted, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 11 with image from Yao et al., 2010
post-vent region decreased flexibility, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
skeletal muscle cell differentiation disrupted, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 12 with image from Yao et al., 2010
retina morphology, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 9 with image from Yao et al., 2010
vertical myoseptum structure, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 12 with image from Yao et al., 2010
retina decreased size, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 8 with image from Yao et al., 2010
retina apoptotic, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 9 with image from Yao et al., 2010
somite fused with somite, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
somite posterior-most region decreased amount, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 11 with image from Yao et al., 2010
brain shape, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
retina layer formation disrupted, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 8 with image from Yao et al., 2010
blood circulation disrupted, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
eye decreased size, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
head hypotrophic, abnormal AB + MO1-atoh8 + MO5-tp53 standard conditions Fig. 4 with image from Yao et al., 2010
otolith decreased size, abnormal AB + MO1-grhl2b + MO5-tp53 standard conditions Fig. 3 from Han et al., 2011
post-vent region curved ventral, abnormal AB + MO1-rer1 + MO5-tp53 standard conditions Fig. 1 from Jurisch-Yaksi et al., 2013
whole organism anterior-posterior axis bent, abnormal AB + MO1-rer1 + MO5-tp53 standard conditions Fig. 1 from Jurisch-Yaksi et al., 2013
somite border deformed, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
blood circulation disrupted, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
post-vent region decreased flexibility, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
extension decreased length, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
pharyngeal arch 3-7 decreased size, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
whole organism anterior-posterior axis curved ventral, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
eye decreased size, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
head hypotrophic, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
brain shape, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
somite fused with somite, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
somite U-shaped, abnormal AB + MO2-atoh8 + MO5-tp53 standard conditions Fig. 5 with image from Yao et al., 2010
whole organism anterior-posterior axis bent, abnormal AB + MO3-rer1 + MO5-tp53 standard conditions Fig. 1 from Jurisch-Yaksi et al., 2013
post-vent region curved ventral, abnormal AB + MO3-rer1 + MO5-tp53 standard conditions Fig. 1 from Jurisch-Yaksi et al., 2013
whole organism col15a1b expression decreased amount, abnormal AB/TU + MO3-col15a1b + MO5-tp53 standard conditions Fig. 6 from Guillon et al., 2016
dorsal/ventral pattern formation disrupted, abnormal TU + MO1-fbxl15 + MO5-tp53 standard conditions Fig. 7 from Cui et al., 2011
trunk decreased length, abnormal TU + MO1-fbxl15 + MO5-tp53 standard conditions Fig. 7 from Cui et al., 2011
trunk increased curvature, abnormal TU + MO1-fbxl15 + MO5-tp53 standard conditions Fig. 7 from Cui et al., 2011
whole organism wholly dorsalized, abnormal TU + MO1-fbxl15 + MO5-tp53 standard conditions Fig. 7 from Cui et al., 2011
granulocyte decreased amount, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
hematopoietic stem cell differentiation disrupted, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
hematopoietic stem cell decreased amount, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
erythroid lineage cell decreased amount, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
hemopoiesis disrupted, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
hemangioblast cell differentiation disrupted, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
common lymphoid progenitor decreased amount, abnormal TU + MO5-etv5a + MO5-tp53 standard conditions Fig. 2 from Chen et al., 2013
whole organism sod1 expression decreased amount, abnormal WT + MO1-atp7a + MO5-tp53 standard conditions Fig. 1 from Chen et al., 2011
head apoptotic, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
spinal cord opaque, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
integument rough, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
trunk curved dorsal, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
spinal cord apoptotic, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
head opaque, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
eye decreased size, abnormal WT + MO1-cenph + MO2-cenph + MO5-tp53 standard conditions Fig. 3 from Zhao et al., 2010
mouth open, abnormal WT + MO1-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
neural tube morphology, abnormal WT + MO1-fbxl18 + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
sclerotome structure, abnormal WT + MO1-fbxl18 + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
trunk truncated, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
somite shape, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
somite increased size, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
whole organism anterior-posterior axis truncated, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
convergent extension involved in gastrulation disrupted, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
whole organism anterior-posterior axis increased width, abnormal WT + MO1-iqgap3 + MO5-tp53 standard conditions Fig. 5 from Fang et al., 2015
caudal fin curved, abnormal WT + MO1-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
trunk posterior region decreased size, abnormal WT + MO1-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin decreased thickness, abnormal WT + MO1-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
whole organism wholly dorsalized, abnormal WT + MO1-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
mouth open, abnormal WT + MO2-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
whole organism decreased length, abnormal WT + MO2-loxa + MO5-tp53 standard conditions Fig. 4 from Reynaud et al., 2008
whole organism morphology, abnormal WT + MO2-loxa + MO5-tp53 standard conditions Fig. 4 from Reynaud et al., 2008
optic tectum structure, abnormal WT + MO2-mmp2 + MO5-tp53 standard conditions Fig. S2 with image from Janssens et al., 2013
retinal ganglion cell axon guidance disrupted, abnormal WT + MO2-mmp2 + MO5-tp53 standard conditions Fig. S2 with image from Janssens et al., 2013
eye decreased diameter, abnormal WT + MO2-mmp2 + MO5-tp53 standard conditions Fig. S2 with image from Janssens et al., 2013
whole organism decreased length, abnormal WT + MO2-mmp2 + MO5-tp53 standard conditions Fig. S2 with image from Janssens et al., 2013
whole organism wholly dorsalized, abnormal WT + MO2-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin curved, abnormal WT + MO2-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
trunk posterior region decreased size, abnormal WT + MO2-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin decreased thickness, abnormal WT + MO2-ppp4cb + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
yolk swollen, abnormal WT + MO2-prmt8b + MO5-tp53 standard conditions Fig. S1 with image from Lin et al., 2013
brain malformed, abnormal WT + MO2-prmt8b + MO5-tp53 standard conditions Fig. S1 with image from Lin et al., 2013
eye decreased size, abnormal WT + MO2-prmt8b + MO5-tp53 standard conditions Fig. S1 with image from Lin et al., 2013
heart edematous, abnormal WT + MO2-prmt8b + MO5-tp53 standard conditions Fig. S1 with image from Lin et al., 2013
post-vent region curved, abnormal WT + MO2-prmt8b + MO5-tp53 standard conditions Fig. S1 with image from Lin et al., 2013
neural tube morphology, abnormal WT + MO2-tgfb2 + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
sclerotome structure, abnormal WT + MO2-tgfb2 + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
neural tube morphology, abnormal WT + MO2-tle3a + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
sclerotome structure, abnormal WT + MO2-tle3a + MO5-tp53 standard conditions Fig. 5 from Lee et al., 2017
trunk posterior region decreased size, abnormal WT + MO3-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin decreased thickness, abnormal WT + MO3-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin curved, abnormal WT + MO3-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
whole organism wholly dorsalized, abnormal WT + MO3-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
retinal ganglion cell decreased amount, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
retinal ganglion cell axon guidance disrupted, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 8 with image from Janssens et al., 2013
retina layer formation disrupted, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
retina has fewer parts of type amacrine cell, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
cranial nerve II hypoplastic, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
cell proliferation involved in compound eye morphogenesis increased occurrence, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 7 with image from Janssens et al., 2013
neural retina development delayed, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
retina lacks all parts of type amacrine cell, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
Muller cell decreased amount, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
Meckel's cartilage malformed, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 4 with image from Janssens et al., 2013
retina layer formation delayed, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
eye decreased size, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 5 with image from Janssens et al., 2013
retina morphology, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
ciliary marginal zone increased size, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 7 with image from Janssens et al., 2013
ceratohyal cartilage malformed, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 4 with image from Janssens et al., 2013
retina proliferative region increased size, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 7 with image from Janssens et al., 2013
retinal cone cell decreased amount, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 6 with image from Janssens et al., 2013
eye decreased diameter, abnormal WT + MO4-mmp14a + MO5-tp53 standard conditions Fig. 5 with imageFig. 9 with image from Janssens et al., 2013
caudal fin decreased thickness, abnormal WT + MO4-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
trunk posterior region decreased size, abnormal WT + MO4-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
caudal fin curved, abnormal WT + MO4-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
whole organism wholly dorsalized, abnormal WT + MO4-ppp4ca + MO5-tp53 standard conditions Fig. 1 with image from Jia et al., 2012
eye decreased size, abnormal WT + MO5-mmp14a + MO5-tp53 standard conditions Fig. 5 with image from Janssens et al., 2013
eye decreased diameter, abnormal WT + MO5-mmp14a + MO5-tp53 standard conditions Fig. 5 with image from Janssens et al., 2013
cranial nerve II decreased thickness, abnormal rw021Tg + MO4-mmp14a + MO5-tp53 standard conditions Fig. 8 with image from Janssens et al., 2013
neural retina development delayed, abnormal rw021Tg + MO4-mmp14a + MO5-tp53 standard conditions Fig. 7 with image from Janssens et al., 2013
neural retina development delayed, abnormal rw021Tg + MO5-mmp14a + MO5-tp53 standard conditions Fig. 7 with image from Janssens et al., 2013
neural crest cell migration disrupted, abnormal y1Tg + MO1-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
pharyngeal arch cranial neural crest mislocalised, abnormal y1Tg + MO1-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
neural crest cell migration disrupted, abnormal y1Tg + MO2-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
pharyngeal arch cranial neural crest mislocalised, abnormal y1Tg + MO2-faf1 + MO5-tp53 standard conditions Fig. 2 from Ghassibe-Sabbagh et al., 2011
posterior lateral line neuromast decreased amount, abnormal zf106Tg + MO1-smad5 + MO5-tp53 standard conditions Fig. 5 from Xing et al., 2015
posterior lateral line neuromast far from posterior lateral line neuromast, abnormal zf106Tg + MO1-smad5 + MO5-tp53 standard conditions Fig. 5 from Xing et al., 2015
posterior lateral line neuromast far from posterior lateral line neuromast, abnormal zf106Tg + MO4-tgfb1a + MO5-tp53 standard conditions Fig. 1 from Xing et al., 2015
posterior lateral line neuromast decreased amount, abnormal zf106Tg + MO4-tgfb1a + MO5-tp53 standard conditions Fig. 1 from Xing et al., 2015
posterior lateral line neuromast irregular spatial pattern, abnormal zf106Tg + MO4-tgfb1a + MO5-tp53 standard conditions Fig. 1 from Xing et al., 2015
head apoptotic, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
trunk curved dorsal, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
brain apoptotic, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
spinal cord opaque, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
eye decreased size, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
head opaque, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
spinal cord apoptotic, abnormal cenphtsu055Gt/tsu055Gt + MO5-tp53 standard conditions Fig. 5 from Zhao et al., 2010
vasculature hemorrhagic, abnormal gbf1tsu3994/tsu3994 + MO5-tp53 standard conditions Fig. 9 from Chen et al., 2017
eye decreased diameter, abnormal WT + MO1-mmp14b + MO4-mmp14a + MO5-tp53 standard conditions Fig. 9 with image from Janssens et al., 2013
retinal ganglion cell axon guidance disrupted, abnormal WT + MO2-mmp2 + MO4-mmp14a + MO5-tp53 standard conditions Fig. 10 with image from Janssens et al., 2013
OTHER MO5-tp53 MORPHOLINO PAGESNo links to external sites
CITATIONS (30)