Image
|
Figure Caption
Fig. 2
Selinexor and eltanexor treatment do not affect the birth of haematopoietic stem and progenitor cells (HSPCs) from the aorta-gonad-mesonephros (AGM) region. (A) Embryos with the indicated genotypes were treated with either dimethylsulfoxide (DMSO), selinexor (100 nM) or eltanexor (250 nM) dissolved in fish water from 1 to 2 days post fertilisation (dpf). Whole-mount in situ hybridisation was performed using a riboprobe for c-myb at 2 dpf and images were taken (overall magnification: 5×). Insets in each of the image magnify staining in the AGM region (magnification in the inset: 11.25×). (B) Quantification of cells with c-myb expression in the AGM region, as shown in panel A.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Br. J. Haematol.