ZFIN Image: Rodenas et al., 2023, FIGURE 7

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Figure Caption

FIGURE 7

Venetoclax reduces Caco-2-HPN cell invasion in zebrafish larvae. (A) Experimental design of the zebrafish larvae xenotransplantation experiments and representative pictures of no invaded and invaded larvae showing red-labelled Caco-2 cells at the injection site (arrow) and several invasion foci (arrowheads). (B) Evaluation of invasion score 3 days after injection in the yolk sac of 2-dpf casper zebrafish larvae. The results showed are a pool of three different experiments. dpf, days post-fertilization; ***: p-value < 0.001; n, number of larvae per treatment; CACO WT, Caco-2 cells with hepsin basal expression; CACO HPN, Caco-2 cells overexpressing hepsin; HPN + V, Caco-2 cells overexpressing hepsin pretreated with venetoclax.

Acknowledgments

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