ZFIN Image: Guo et al., 2020, Figure 4

Image

Figure Caption

Figure 4

Effect of mutant KIF1A on the miniature excitatory post-synaptic currents (mEPSCs) and miniature inhibitory post-synaptic currents (mIPSCs) of primary cultured neurons. (A) Representative trace of mEPSCs from cultured hippocampal neurons transfected with the mutant or wild-type KIF1A plasmid at a holding potential of −70 mV. (B, C) Bar graph analysis of the mEPSC frequency and amplitude (n = 8 neurons in each group, ***p < 0.001, Student's t test). (D) Representative trace of mIPSCs from cultured hippocampal neurons transfected with the mutant or wild-type KIF1A plasmids at a holding potential of −70 mV. (E, F) Bar graph analysis of the mIPSC frequency and amplitude [n = 10 in the mutant group and 8 in the wild type (WT) group, Student's t test].

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Genet