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Fig. 8 Ntl but not gata5 is positively regulated by FGF. A,C,E are 50% epiboly embryos hybridised with a probe to ntl. (A) Uninjected (uninj) embryo. (C) Injection of eFGF RNA causes widespread expression of ntl. (E) Injection of RNA encoding dominant negative FGF receptor, XFD. Where the β-gal tracer overlaps the germ ring, ntl expression is abolished in all but a single tier of cells closest to the blastoderm margin. B,D,F are embryos hybridised to gata5 probe. (B) uninjected embryo, (D) injected with eFGF, (F) injected with XFD. Neither eFGF nor XFD affect gata5 expression. Scale bar, 150 μm.
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