ZFIN ID: ZDB-GENE-980526-340
Gene Name: GATA binding protein 5
Gene Symbol: gata5    Nomenclature History

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Previous Names: gta5, cb634 (1), fau, faust

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Exhibits DNA binding activity and DNA-binding transcription factor activity. Involved in several processes, including Kupffer's vesicle development; animal organ development; and post-embryonic foregut morphogenesis. Localizes to nucleus. Is expressed in several structures, including DEL; cardiovascular system; digestive system; mesoderm; and presumptive structure. Orthologous to human GATA5 (GATA binding protein 5).
Genome Resources: Alliance (1),  Gene:30482 (1),  Ensembl(GRCz11):ENSDARG00000017821 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
hu3392 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • s26 Unknown Unknown Unknown SPONTANEOUS
    sa17489 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24255 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa43913 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • tm236a Point Mutation Intron 3 Cryptic Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-gata5
    3
    CRISPR2-gata5
    1
    MO1-gata5 N/A 13
    MO2-gata5 N/A 6
    MO3-gata5 N/A 3
    MO4-gata5 N/A 1
    MO5-gata5 N/A 1
    DISEASE ASSOCIATED WITH gata5 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Congenital heart defects, multiple types, 5 617912
    DISEASE ASSOCIATED WITH gata5 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process regulation of gene expression (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 33)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gata5-201 (1)    Ensembl 2310
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gata5
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(gata5-E1B:EGFP) E1Bgata5 EGFP Danio rerio 1 2
    TgBAC(gata5:EGFP) gata5 EGFP Danio rerio 1 8
    tgbac(gata5:lifeact-egfp) gata5 EGFPLIFEACT Danio rerio 1 1
    TgBAC(gata5:LOXP-mCherry-LOXP-NLS-EGFP) gata5 EGFPmCherryNLS Danio rerio 1 6
    MARKER RELATIONSHIPS
    gata5 Contained in: [BAC] DKEYP-73A2 (1)
    gata5 Encodes: [EST] cb634 (1) (order this)
    [cDNA] MGC:136430 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131235 (1) 2204 nt
    Genomic GenBank:BX323800 (1) 195592 nt
    Select Tool
    Polypeptide UniProtKB:Q1JQ00 (1) 383 aa
    Sequence Information (all 15)
    ORTHOLOGY for gata5 ( Chr: 23 )
    CITATIONS (180)