ZFIN ID: ZDB-GENE-990415-38
Gene Name: connexin 43.4
Gene Symbol: cx43.4    Nomenclature History

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Previous Names: cb232 (1), gja7, wu:fc46h11 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Predicted to have gap junction channel activity. Predicted to be involved in cell-cell signaling. Predicted to localize to connexin complex. Is expressed in several structures, including central nervous system; immature eye; mesoderm; neural tube; and tail bud. Orthologous to human GJC1 (gap junction protein gamma 1).
Genome Resources: Alliance (1),  Gene:30276 (1),  Ensembl(GRCz11):ENSDARG00000007099 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la027032Tg Transgenic Insertion Unknown Unknown DNA
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
CRISPR1-cx43.4
2
MO1-cx43.4 N/A 1
DISEASE ASSOCIATED WITH cx43.4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH cx43.4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cell communication (more)
Cellular Component cell junction (more)
Molecular Function gap junction channel activity (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA cx43.4-201 (1)    Ensembl 2391
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM cx43.4 No data available
MARKER RELATIONSHIPS
cx43.4 Contained in: [BAC] DKEY-79P17 (order this)
cx43.4 Encodes: [EST] cb232 (1) (order this), eu377 (1), fc46h11 (1)
[cDNA] MGC:55273 (1), MGC:191652 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_131069 (1) 2390 nt
Genomic GenBank:CR394556 (1) 136863 nt
Select Tool
Polypeptide UniProtKB:B0UYC0 (1) 380 aa
Sequence Information (all 24)
ORTHOLOGY for cx43.4 ( Chr: 9 )
CITATIONS (45)