Gene

rho

ID
ZDB-GENE-990415-271
Name
rhodopsin
Symbol
rho Nomenclature History
Previous Names
  • Rh
  • opsin-like gene
  • rh1.1 (1)
  • rod opsin
  • wu:fi06d11 (1)
  • zfo2
  • zfrho
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits G protein-coupled photoreceptor activity and retinal binding activity. Involved in absorption of visible light. Localizes to photoreceptor outer segment. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 1; fundus albipunctatus; night blindness; retinitis pigmentosa; and retinitis pigmentosa 4. Is expressed in several structures, including digestive system; endocrine system; photoreceptor cell; presumptive neural retina; and visual system. Orthologous to human RHO (rhodopsin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
138 figures from 96 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rho Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stationary night blindness autosomal dominant 1 Alliance Night blindness, congenital stationary, autosomal dominant 1 610445
fundus albipunctatus Alliance Retinitis punctata albescens 136880
retinitis pigmentosa 4 Alliance Retinitis pigmentosa 4, autosomal dominant or recessive 613731
Associated With rho Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR027430 Visual pigments (opsins) retinal binding site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Domain IPR019477 Rhodopsin, N-terminal
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000732 Rhodopsin
Family IPR001760 Opsin
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Opsin Rhodopsin Rhodopsin, N-terminal Visual pigments (opsins) retinal binding site
UniProtKB:B8JMK8 354
UniProtKB:P35359 354
UniProtKB:H7BRV1 286
UniProtKB:B9TRZ2 161
UniProtKB:Q8AV67 354
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-rho monoclonal IgG1 Mouse
  • IHC
Sigma-Aldrich
Santa Cruz Biotechnology, Inc.
Millipore
Abcam plc
38
Ab5-rho monoclonal Mouse
  • IHC
  • WB
Abcam plc
Millipore
34
Ab1-rho monoclonal Mouse
  • IHC
31
Ab4-rho monoclonal Mouse
  • IHC
5
Ab2-rho polyclonal Rabbit
  • IHC
20
Ab10-rho
ABclonal
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations