Gene

rho

ID
ZDB-GENE-990415-271
Name
rhodopsin
Symbol
rho Nomenclature History
Previous Names
  • Rh
  • opsin-like gene
  • rh1.1 (1)
  • rod opsin
  • wu:fi06d11 (1)
  • zfo2
  • zfrho
Type
protein_coding_gene
Location
Chr: 8 Mapping Details/Browsers
Description
Exhibits G protein-coupled photoreceptor activity and retinal binding activity. Involved in absorption of visible light. Localizes to photoreceptor outer segment. Is expressed in several structures, including digestive system; endocrine system; photoreceptor cell; presumptive neural retina; and visual system. Used to study retinitis pigmentosa. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 1; fundus albipunctatus; night blindness; retinitis pigmentosa; and retinitis pigmentosa 4. Orthologous to human RHO (rhodopsin).
Genome Resources
Note
None
Expression
All Expression Data
131 figures from 90 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With rho Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital stationary night blindness autosomal dominant 1 Alliance Night blindness, congenital stationary, autosomal dominant 1 610445
fundus albipunctatus Alliance Retinitis punctata albescens 136880
retinitis pigmentosa 4 Alliance Retinitis pigmentosa 4, autosomal dominant or recessive 613731
Associated With rho Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR027430 Visual pigments (opsins) retinal binding site
Domain IPR017452 GPCR, rhodopsin-like, 7TM
Domain IPR019477 Rhodopsin, N-terminal
Family IPR000276 G protein-coupled receptor, rhodopsin-like
Family IPR000732 Rhodopsin
Family IPR001760 Opsin
Domain Details Per Protein
Protein Length GPCR, rhodopsin-like, 7TM G protein-coupled receptor, rhodopsin-like Opsin Rhodopsin Rhodopsin, N-terminal Visual pigments (opsins) retinal binding site
UniProtKB:B9TRZ2 161
UniProtKB:H7BRV1 286
UniProtKB:P35359 354
UniProtKB:Q8AV67 354
UniProtKB:B8JMK8 354
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab3-rho monoclonal IgG1 Mouse
  • IHC
Sigma-Aldrich
Santa Cruz Biotechnology, Inc.
Millipore
Abcam plc
31
Ab5-rho monoclonal Mouse
  • IHC
  • WB
Millipore
Abcam plc
29
Ab1-rho monoclonal Mouse
  • IHC
29
Ab4-rho monoclonal Mouse
  • IHC
5
Ab2-rho polyclonal Rabbit
  • IHC
20
Ab10-rho
ABclonal
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations